Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 17/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128600 | 0.84 | TRPA1 (0.52) | P2RX3KDM4EALDH1A1HPGD | |
| SCHEMBL30128680 | 0.81 | MCL1 (0.50) | P2RX3 | |
| SCHEMBL30129021 | 0.81 | GRK2 (0.49) | P2RX3 | |
| SCHEMBL30128619 | 0.81 | GRK2 (0.52) | P2RX3MAPT | |
| SCHEMBL30128609 | 0.81 | GRK2 (0.49) | P2RX3KDM4E | |
| SCHEMBL14978256 | 0.78 | KMT2A (0.53) | P2RX3KDM4E | |
| SCHEMBL14978257 | 0.78 | P2RX3 (0.53) | P2RX3KDM4E | |
| SCHEMBL28389854 | 0.78 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL31352625 | 0.78 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL30128668 | 0.78 | L3MBTL1 (0.58) | P2RX3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |