Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 4/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632005 | 0.78 | ADORA1 (0.62) | HSD17B1HSD17B2PIK3CGADORA1ABL1 | |
| SCHEMBL30129595 | 0.77 | RXFP1 (0.44) | HSD17B1HSD17B2PIK3CGADORA1SYK | |
| SCHEMBL29914724 | 0.77 | FTO (0.66) | HSD17B1HSD17B2FTOCYP1A2CYP3A4 | |
| SCHEMBL28430998 | 0.77 | FTO (0.66) | HSD17B1HSD17B2FTOCYP1A2CYP3A4 | |
| SCHEMBL29461710 | 0.74 | HSD17B1 (0.56) | HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29461811 | 0.72 | HSD17B1 (0.58) | HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30260606 | 0.72 | HSD17B2 (0.49) | HSD17B1HSD17B2FTOPIK3CGCYP1A2 | |
| SCHEMBL9160918 | 0.70 | IDO1 (0.45) | HSD17B1HSD17B2FYNBMPR1ATGFBR1 | |
| SCHEMBL9160925 | 0.69 | HSD17B1 (0.45) | HSD17B1HSD17B2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28346658 | 0.69 | FTO (0.39) | FTOCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230069804-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230027684-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20230008867-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230008867-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SNRPA1 | HSD17B1 2388/4885HSD17B2 2816/4885FTO 2943/4885 |
| US-20230027684-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | HSD17B1 2342/4885HSD17B2 2758/4885FTO 3141/4885 |
| US-20230069804-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | HSD17B1 2342/4885HSD17B2 2758/4885FTO 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.