Dimethylamine

Dimethylamine

SCHEMBL3013534

CCN1C(=O)CCC1C.CNC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.47
CHRM4 P08173 3/20 0.47
CHRM5 P08912 3/20 0.47
CHRM1 P11229 3/20 0.47
CHRM3 P20309 3/20 0.47
P2RX7 Q99572 9/20 0.39
PER2 O15055 6/20 0.39
CRY2 Q49AN0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17946144 0.94
SCHEMBL2379257 0.94
SCHEMBL10587336 0.82 CHRM2 (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL3337122 0.78 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL4330615 0.78 CHRM2 (0.49) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL1948450 0.76 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11463019 0.75
SCHEMBL11479479 0.75
SCHEMBL11288962 0.75
SCHEMBL13232234 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100204522-A1 PROCESS FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-12 US disclosed
US-20100197975-A1 PROCESS FOR MAKING DIALKYL ETHERS FROM ALCOHOLS E.I. DU PONT DE NEMOURS & COMPANY (DE) 2010-08-05 US disclosed
US-20100179355-A1 PROCESSES FOR MAKING DIALKYL ETHERS FROM ALCOHOLS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-15 US disclosed
US-7625941-B2 N-substituted pyrrolidinone having a separated pendant ammonium cation by a variable length alkyl spacer and fluoroalkyl sulfonate anions; environmentally friendly solvent; catalysts for reactions, including nitration, acylation, esterification, etherification E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-01 US disclosed
EP-1940761-B1 PREPARATION OF POLYTRIMETHYLENE ETHER GLYCOL AND COPOLYMERS THEREOF DU PONT (US) 2009-05-06 EP disclosed
EP-1951647-A2 OLEFIN ISOMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-08-06 EP disclosed
US-7405330-B2 Preparation of polytrimethylene ether glycol and copolymers thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-29 US disclosed
US-7402711-B2 Preparation of poly(tetramethylene) glycol E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-22 US disclosed
EP-1940761-A1 PREPARATION OF POLYTRIMETHYLENE ETHER GLYCOL AND COPOLYMERS THEREOF E.I.Du pont de nemours and company (US) 2008-07-09 EP disclosed
US-7314962-B2 Alkylation of aromatic compounds E. I. DU PONT DE NEMOURS & CO. (US) 2008-01-01 US disclosed
US-20070123737-A1 Preparation of polytrimethylene ether glycol and copolymers thereof E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-31 US disclosed
WO-2007050490-A2 OLEFIN ISOMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-03 WO disclosed
US-20070100192-A1 Olefin isomerization E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-03 US disclosed
WO-2007038362-A1 PREPARATION OF POLYTRIMETHYLENE ETHER GLYCOL AND COPOLYMERS THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-05 WO disclosed
US-20070066853-A1 Preparation of poly(tetramethylene) glycol E. I. DU PONT DE NEMOURS AND COMPANY 2007-03-22 US disclosed
US-20070066834-A1 Ionic liquids E. I. DU PONT DE NEMOURS AND COMPANY 2007-03-22 US disclosed
US-7157588-B2 Ionic liquids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-01-02 US disclosed
US-20060235230-A1 Based on an N-substituted pyrrolidinone having a pendant ammonium cation that is separated from the pyrrolidone ring by a variable length alkyl spacer; use as solvents, catalysts; can be readily prepared from levulinic acid or derivatives obtained from the hydrolysis of inexpensive biomass feedstock THE CHEMOURS COMPANY FC, LLC 2006-10-19 US disclosed
US-20060235249-A1 Alkylation of aromatic compounds E. I. DU PONT DE NEMOURS AND COMPANY 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066853-A1 Preparation of poly(tetramethylene) glycol PARG, PUF60, TPR CHRM2 4672/4885CHRM4 4575/4885CHRM5 3941/4885
US-20100179355-A1 PROCESSES FOR MAKING DIALKYL ETHERS FROM ALCOHOLS ADH1C, DAGLA, DCLK1 CHRM2 3356/4885CHRM4 3134/4885CHRM5 3600/4885
US-20070066834-A1 Ionic liquids NUP205, PML, AQP4 CHRM2 4192/4885CHRM4 4264/4885CHRM5 3308/4885
US-20070123737-A1 Preparation of polytrimethylene ether glycol and copolymers thereof PARG, PTGES3, PGD CHRM2 3146/4885CHRM4 3594/4885CHRM5 3264/4885
US-20060235249-A1 Alkylation of aromatic compounds TYR, ALK, AHR CHRM2 1525/4885CHRM4 752/4885CHRM5 941/4885
US-20060235230-A1 Based on an N-substituted pyrrolidinone having a pendant ammonium cation that is separated from the pyrrolidone ring by a variable length alkyl spacer; use as solvents, catalysts; can be readily prepared from levulinic acid or derivatives obtained from the hydrolysis of inexpensive biomass feedstock ALAD, ASS1, ADSL CHRM2 3911/4885CHRM4 4063/4885CHRM5 2812/4885
US-20070100192-A1 Olefin isomerization OSBP, OXER1, OSBPL3 CHRM2 3157/4885CHRM4 2323/4885CHRM5 3238/4885
US-20100204522-A1 PROCESS FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL EBP, PPIP5K2, PCBP1 CHRM2 4171/4885CHRM4 3516/4885CHRM5 3580/4885
US-20100197975-A1 PROCESS FOR MAKING DIALKYL ETHERS FROM ALCOHOLS ADH1C, DCLK1, DCLK3 CHRM2 1763/4885CHRM4 1254/4885CHRM5 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.