Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301433 | 0.90 | TSHR (0.51) | KMT2ATSHRALDH1A1HPGDKDM4E | |
| SCHEMBL14889325 | 0.84 | TSHR (0.47) | KMT2ATSHRALDH1A1HPGDKDM4E | |
| SCHEMBL5837295 | 0.81 | HPGD (0.39) | MEN1KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL12449353 | 0.79 | KDM4C (0.42) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL617437 | 0.78 | MAPT (0.43) | TSHREPHX2ALDH1A1MMP8SMN1; SMN2 | |
| SCHEMBL302645 | 0.78 | MAPT (0.50) | TSHREPHX2ALDH1A1HPGDMMP8 | |
| SCHEMBL13847041 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2ATSHREPHX2ALDH1A1 | |
| SCHEMBL4881440 | 0.75 | TSHR (0.50) | MEN1KMT2ATSHREPHX2ALDH1A1 | |
| SCHEMBL291397 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL3240918 | 0.74 | MMP8 (0.34) | KMT2ATSHRALDH1A1MMP8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111084419-B | Smoking article mouthpiece with cooling agent envelope | 菲利普莫里斯生产公司 | 2023-03-17 | — | — | CN | claimed |
| EP-2844094-B1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS SA (CH) | 2021-01-27 | — | — | EP | claimed |
| CN-111084419-A | Smoking article mouthpiece with cooling agent inclusion compound | 菲利普莫里斯生产公司 | 2020-05-01 | — | — | CN | claimed |
| US-20180220699-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-08-09 | — | — | US | claimed |
| US-9949505-B2 | Smoking article mouthpiece with cooling agent inclusion complex | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-04-24 | — | — | US | claimed |
| CN-104703492-A | Smoking article mouthpiece with cooling agent inclusion compound | PHILIP MORRIS PRODUCTS SA | 2015-06-10 | — | — | CN | claimed |
| US-20150107608-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS S.A. (CH) | 2015-04-23 | — | — | US | claimed |
| EP-2844094-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | Philip Morris Products S.A. (CH) | 2015-03-11 | — | — | EP | claimed |
| WO-2013164706-A1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS S.A. (CH) | 2013-11-07 | — | — | WO | claimed |
| US-12601929-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2026-04-14 | — | — | US | disclosed |
| US-12414906-B2 | Compositions and methods for treating hot flashes | THE PROCTER & GAMBLE COMPANY (US) | 2025-09-16 | — | — | US | disclosed |
| EP-4388349-B1 | CONTACT LENS | COOPERVISION INT LTD (GB) | 2025-03-12 | — | — | EP | disclosed |
| US-12153288-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-11-26 | — | — | US | disclosed |
| US-20240264469-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-08-08 | — | — | US | disclosed |
| WO-2011159935-A1 | CHEWING GUM CONTAINING COMBINATIONS OF PHYSIOLOGICAL COOLING AGENTS | WM. WRIGLEY JR. COMPANY (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011159927-A1 | CHEWING GUM PRODUCTS CONTAINING ETHYL ESTER OF N-[[5-METHYL-2-(1-METHYLETHYL)-CYCLOHEXYL] CARBONYL] GLYCINE | WM. WRIGLEY JR. COMPANY (US) | 2011-12-22 | — | — | WO | disclosed |
| US-20080293821-A1 | Cooling compositions | MOZA ASHOK K | 2008-11-27 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-7030273-B1 | Compounds with physiological cooling effect | QAROMA, INC (US) | 2006-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12601929-B2 | Contact lens | TRPM8, TRPM7, TRPM5 | MEN1 2563/4885KMT2A 1502/4885TSHR 4239/4885 |
| US-12414906-B2 | Compositions and methods for treating hot flashes | ELOVL5, ELOVL3, HCN3 | MEN1 1898/4885KMT2A 4355/4885TSHR 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.