Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Valeric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.94 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.54 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | FABP3 | P05413 | 5/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valeric Acid SCHEMBL30368938 | 0.97 | CA1 (1.00) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL109106 | 0.97 | — | — | |
| Valeric Acid SCHEMBL150677 | 0.97 | CA1 (0.89) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL29157748 | 0.94 | CA1 (0.94) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL29364939 | 0.94 | CA1 (0.94) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL28529950 | 0.94 | CA1 (0.84) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL9898725 | 0.94 | CA1 (0.84) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL11815174 | 0.94 | CA1 (0.94) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL2207479 | 0.92 | CA1 (0.89) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL5047413 | 0.92 | CA1 (0.89) | CA1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164687-B | Method of inserting a lubricant-free stopper into a lubricant-free syringe and assembly system | W.L.戈尔及同仁股份有限公司 | 2023-02-17 | — | — | CN | disclosed |