Cyclo(Prolylglycyl)

Cyclo(Prolylglycyl)

SCHEMBL3016264

O=C1NCC(=O)N2CCCC12

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 4/20 0.48
MAPT P10636 3/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
PARP1 P09874 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
PPIA P62937 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclo(Prolylglycyl) SCHEMBL4247464 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL30768150 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL21736594 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL21736595 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTGAAKMT2A
Cyclo(Prolylglycyl) SCHEMBL4243772 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL1189351 0.94 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL3519704 0.94 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL3519708 0.94 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL17516644 0.93 KDM4E (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL464685 0.93 KDM4E (0.43) ALDH1A1KDM4EMAPTGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120129468-A Composition for inhibiting amyloid beta accumulation 三得利控股株式会社 2025-06-10 CN claimed
CN-119403556-A Composition for immunomodulation 三得利控股株式会社 2025-02-07 CN claimed
WO-2024158103-A1 COMPOSITION CONTAINING STREPTOCOCCUS SP. STRAIN FOR PREVENTION, ALLEVIATION, OR TREATMENT OF SKIN DISEASES 코스맥스 주식회사 2024-08-02 WO claimed
CN-118126045-A Method for preparing cycloglycyl proline from collagen oligopeptide and application of method 中国海洋大学三亚海洋研究院 2024-06-04 CN claimed
CN-117567566-B Liquid phase synthesis process of cyclohexapeptide-9 山东济肽生物科技有限公司 2024-05-03 CN claimed
CN-117567566-A Liquid phase synthesis process of cyclohexapeptide-9 山东济肽生物科技有限公司 2024-02-20 CN claimed
WO-2024004931-A1 IMMUNOMODULATION COMPOSITION サントリーホールディングス株式会社 2024-01-04 WO claimed
CN-116685343-A Use of cyclic dipeptides for the manufacture of agents that inhibit cognitive decline or improve cognitive dysfunction 三得利控股株式会社 2023-09-01 CN claimed
EP-4081303-A1 COMPOSITION CONTAINING CYCLIC DIPEPTIDE, PURINE NUCLEOSIDE AND/OR AMINO ACID, AND CHICKEN EXTRACT, PRODUCTION METHOD THEREOF, AND USE OF CYCLIC DIPEPTIDE, PURINE NUCLEOSIDE AND/OR AMINO ACID, AND CHICKEN EXTRACT Suntory Holdings Limited (JP) 2022-11-02 EP claimed
CN-115066273-A Composition comprising cyclic dipeptide, purine nucleoside and/or amino acid and chicken extract, method for producing same and use of cyclic dipeptide, purine nucleoside and/or amino acid and chicken extract 三得利控股株式会社 2022-09-16 CN claimed
EP-2594134-B1 USE OF AN AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT REPUBLIC OF KOREA (MANAGEMENT: RURAL DEV ADMINISTRATION) (KR) 2017-08-02 EP claimed
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Kongju National University Industry- University Cooperation Foundation (KR) 2013-07-25 US claimed
EP-2594134-A2 AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Republic of Korea (Management: Rural Development Administration) (KR) 2013-05-22 EP claimed
US-20100203154-A1 Elasmobranch-Repelling Compounds, Methods of Use and Devices STROUD ERIC MATTHEW 2010-08-12 US claimed
EP-0751779-B1 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORP (US) 2001-12-19 EP claimed
EP-0751779-A4 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORP (US) 1998-12-09 EP claimed
EP-0751779-A1 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORPORATION (US) 1997-01-08 EP claimed
WO-1995000165-A1 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORPORATION (US) 1995-01-05 WO claimed
EP-4743102-A1 COLLAGEN PEPTIDE COMPOSITION AND USE THEREOF IN AMELIORATING NEUROLOGICAL CONDITIONS AND FIBROSIS Rousselot BV (BE) 2026-05-20 EP disclosed
US-3920660-A Tetrahydropyrrolo{8 1,2-a{9 pyrazine-1(2H),4(3H)-diones LEPETIT SPA 1975-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100203154-A1 Elasmobranch-Repelling Compounds, Methods of Use and Devices ELOC, ELOVL3, ELOVL6 ALDH1A1 2284/4885KDM4E 1578/4885MAPT 3604/4885
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT HDHD5, DAZAP1, MAPKAPK5 ALDH1A1 3568/4885KDM4E 1291/4885MAPT 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.