SCHEMBL30189641

SCHEMBL30189641

CN1[C@@H]2CCC[C@@]1(c1ccccc1I)CC2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.33
GRIN2B Q13224 1/20 0.33
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7121073 0.82 OPRL1 (0.35) KCNH2GRIN2BOPRM1OPRD1OPRK1
SCHEMBL1843463 0.78 ALDH1A1 (0.34) KCNH2GRIN2B
SCHEMBL633353 0.78 SLC6A2 (0.43) KCNH2GRIN2BOPRM1OPRD1SLC6A2
SCHEMBL29435414 0.76 HTR6 (0.40) KCNH2SLC6A2SLC6A4SLC6A3
SCHEMBL7968110 0.76 HTR6 (0.40) KCNH2SLC6A2SLC6A4SLC6A3
SCHEMBL8812050 0.75 OPRM1 (0.36) GRIN2BOPRM1OPRK1SLC6A2SLC6A4
SCHEMBL7356160 0.73 CHRNB4 (0.33)
SCHEMBL7458612 0.70 OPRM1 (0.34) OPRM1
SCHEMBL27422130 0.70 OPRM1 (0.34) OPRM1
SCHEMBL4781128 0.69 HSD11B1 (0.34) GRIN2BOPRK1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111574515-B Preparation method and purification method of organic fluorinated aliphatic compound 财团法人峨山社会福祉财团 2023-01-10 CN disclosed