Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435414 | 1.00 | HTR6 (0.40) | HTR6KDM4EATMMAPTSLC6A4 | |
| SCHEMBL9020233 | 0.76 | RAB9A (0.38) | KDM4EALDH1A1TP53SMN1; SMN2KMT2A | |
| SCHEMBL30189641 | 0.76 | KCNH2 (0.33) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL7121073 | 0.73 | OPRL1 (0.35) | KMT2AMEN1CYP3A4KCNH2 | |
| SCHEMBL633353 | 0.72 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL1413413 | 0.70 | CYP2D6 (0.46) | KDM4EATMMAPTSLC6A4SLC6A2 | |
| SCHEMBL1843463 | 0.70 | ALDH1A1 (0.34) | KDM4EALDH1A1KCNH2NPSR1 | |
| SCHEMBL21219851 | 0.69 | HTR3E (0.54) | MAPTSLC6A4ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL22864444 | 0.67 | ATM (0.48) | KDM4EATMMAPTSLC6A4SLC6A2 | |
| SCHEMBL28595479 | 0.67 | MAPT (0.52) | KDM4EATMMAPTSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014374-A2 | PROCESSES FOR THE PREPRATION OF EXO- AND ENDO-INDOLOTROPANES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |