Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 1.00 |
| ▸ | TEAD4 | Q15561 | 1/20 | 1.00 |
| ▸ | TEAD2 | Q15562 | 1/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22731881 | 1.00 | YAP1 (1.00) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL24142302 | 0.88 | YAP1 (0.79) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL14853341 | 0.87 | YAP1 (0.77) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL29504977 | 0.85 | MPO (0.74) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL22719595 | 0.85 | MPO (0.74) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL9522037 | 0.85 | YAP1 (0.74) | YAP1TEAD4TEAD2RXFP1LMNA | |
| Flufenamic Acid SCHEMBL17497 | 0.83 | RXFP1 (0.75) | YAP1TEAD4TEAD2RXFP1LMNA | |
| Flufenamic Acid SCHEMBL29356958 | 0.83 | RXFP1 (0.75) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL22731809 | 0.83 | YAP1 (0.71) | YAP1TEAD4TEAD2RXFP1LMNA | |
| SCHEMBL9268782 | 0.83 | RXFP1 (0.78) | YAP1TEAD4TEAD2RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023277135-A1 | METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF | 住友化学株式会社 | 2023-01-05 | — | — | WO | disclosed |