Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31622406 | 1.00 | ARG1 (0.37) | ARG1ARG2FDPSPTPN11HRH4 | |
| SCHEMBL30833221 | 0.88 | PTPN11 (0.40) | ARG1ARG2FDPSPTPN11MEN1 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.76 | LTA4H (0.49) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30201500 | 0.75 | CYP3A4 (0.39) | ARG1ARG2HRH4HRH3ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30201424 | 0.75 | OPRM1 (0.52) | ALDH1A1OPRK1KCNH2L3MBTL1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL30201490 | 0.75 | ARG1 (0.35) | ARG1ARG2HRH4HRH3OPRK1 | |
| Trifluoroacetic Acid SCHEMBL30201532 | 0.75 | DPP4 (0.41) | HRH4HRH3OPRK1KCNH2OPRM1 | |
| Trifluoroacetic Acid SCHEMBL16700919 | 0.72 | FDPS (0.46) | FDPSHRH4HRH3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.72 | ARG1 (0.54) | ARG1ARG2MEN1KMT2AMAPK1 | |
| Trifluoroacetic Acid SCHEMBL30201437 | 0.72 | ARG1 (0.54) | ARG1ARG2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |