Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24951146 | 0.86 | WDR5 (0.47) | MEN1KMT2AF10NFKB1HDAC1 | |
| SCHEMBL30202783 | 0.86 | WDR5 (0.47) | MEN1KMT2AF10NFKB1HDAC1 | |
| SCHEMBL24952254 | 0.77 | RAB9A (0.47) | MEN1KMT2ANFKB1JUNNFKB2 | |
| SCHEMBL24951831 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2ANFKB1ATF1NPC1 | |
| SCHEMBL30202682 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2ANFKB1ATF1NPC1 | |
| SCHEMBL20558390 | 0.76 | XPO1 (0.58) | MEN1KMT2ANFKB1JUNNFKB2 | |
| SCHEMBL22145716 | 0.76 | NPC1 (0.50) | KMT2ANFKB1JUNNFKB2RELA | |
| SCHEMBL20558385 | 0.73 | RXFP1 (0.46) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL20558515 | 0.73 | NFKB1 (0.54) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL20558241 | 0.73 | CHRNA7 (0.44) | F10NFKB1JUNNFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4376845-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | Actelion Pharmaceuticals Ltd (CH) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023007009-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-02-02 | — | — | WO | disclosed |