Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.47 |
| ▸ | CALCR | P30988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634905 | 0.92 | AGTR1 (0.56) | C5AR1AGTR1AGTR2EPHA2NTSR1 | |
| SCHEMBL29429586 | 0.91 | NTSR1 (0.56) | C5AR1AGTR1AGTR2EPHA2NTSR1 | |
| SCHEMBL30082469 | 0.91 | C5AR1 (0.54) | C5AR1AGTR1AGTR2EPHA2NTSR1 | |
| SCHEMBL30116695 | 0.88 | C5AR1 (0.57) | C5AR1AGTR1AGTR2EPHA2NTSR1 | |
| SCHEMBL2030582 | 0.88 | CTSL (0.54) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL2034640 | 0.87 | CTSL (0.49) | C5AR1AGTR1AGTR2CTSLCTSS | |
| SCHEMBL29701260 | 0.86 | C5AR1 (0.60) | C5AR1AGTR1AGTR2NTSR1NTSR2 | |
| SCHEMBL8741230 | 0.85 | C5AR1 (0.59) | C5AR1AGTR1AGTR2NTSR1NTSR2 | |
| SCHEMBL29975776 | 0.85 | AGTR1 (0.57) | C5AR1AGTR1AGTR2NTSR1NTSR2 | |
| SCHEMBL7052378 | 0.85 | AGTR2 (0.65) | C5AR1AGTR1AGTR2EPHA2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285291-A1 | MANUFACTURING OF SYNTHETIC EXOSOMES FOR CNS AND NON-CNS DELIVERY OF THERAPEUTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-14 | — | — | US | disclosed |
| EP-4132584-A1 | MANUFACTURING OF SYNTHETIC EXOSOMES FOR CNS AND NON-CNS DELIVERY OF THERAPEUTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-15 | — | — | EP | disclosed |