Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.48 |
| ▸ | CALCR | P30988 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035184 | 0.92 | OPRM1 (0.48) | CTSLCTSSCTSKCTSHNTSR1 | |
| SCHEMBL2030582 | 0.89 | CTSL (0.54) | CTSLCTSSCTSKCTSHEPHA2 | |
| SCHEMBL29634905 | 0.87 | AGTR1 (0.56) | EPHA2NTSR1AGTR1NTSR2SORT1 | |
| SCHEMBL30230103 | 0.87 | C5AR1 (0.50) | CTSLCTSSCTSKCTSHEPHA2 | |
| SCHEMBL29429586 | 0.86 | NTSR1 (0.56) | EPHA2NTSR1AGTR1NTSR2SORT1 | |
| SCHEMBL30082469 | 0.86 | C5AR1 (0.54) | EPHA2NTSR1AGTR1NTSR2SORT1 | |
| SCHEMBL30116695 | 0.85 | C5AR1 (0.57) | EPHA2NTSR1AGTR1NTSR2SORT1 | |
| SCHEMBL30230017 | 0.83 | OPRM1 (0.58) | CTSLCTSSCTSKCTSHOPRM1 | |
| SCHEMBL11024540 | 0.83 | AGTR1 (0.53) | EPHA2NTSR1AGTR1NTSR2SORT1 | |
| SCHEMBL11024546 | 0.83 | AGTR1 (0.53) | EPHA2NTSR1AGTR1NTSR2SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169291-B2 | Covalent conjugates between endoperoxides and transferrin and lactoferrin receptor-binding agents | UNIVERSITY OF WASHINGTON (US) | 2015-10-27 | — | — | US | disclosed |
| US-20110150830-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | WASHINGTON, UNIVERSITY OF (US) | 2011-06-23 | — | — | US | disclosed |
| US-20070231300-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | WASHINGTON, UNIVERSITY OF (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150830-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | TFRC, LPO, FTH1 | CTSL 497/4885CTSS 456/4885CTSK 851/4885 |
| US-20070231300-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | TFRC, LPO, FTH1 | CTSL 497/4885CTSS 456/4885CTSK 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.