Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSH | P09668 | 1/20 | 0.54 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.53 |
| ▸ | CALCR | P30988 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.52 |
| ▸ | NPY1R | P25929 | 2/20 | 0.52 |
| ▸ | NPY4R | P50391 | 2/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.52 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034640 | 0.89 | CTSL (0.49) | CTSLCTSSCTSKCTSHRAMP3 | |
| SCHEMBL29634905 | 0.88 | AGTR1 (0.56) | F2C5AR1EPHA2NTSR2NTSR1 | |
| SCHEMBL30230103 | 0.88 | C5AR1 (0.50) | CTSLCTSSCTSKCTSHRAMP3 | |
| SCHEMBL29429586 | 0.87 | NTSR1 (0.56) | C5AR1EPHA2NTSR2NTSR1 | |
| SCHEMBL30082469 | 0.87 | C5AR1 (0.54) | F2APLNRC5AR1EPHA2NTSR2 | |
| SCHEMBL18699898 | 0.86 | AGTR1 (0.56) | F2APLNRC5AR1EPHA2NTSR2 | |
| SCHEMBL18699899 | 0.86 | AGTR1 (0.56) | F2APLNRC5AR1EPHA2NTSR2 | |
| SCHEMBL30116695 | 0.86 | C5AR1 (0.57) | APLNRC5AR1NPY5RNPY1RNPY4R | |
| Trv-120027 SCHEMBL17274209 | 0.85 | AGTR1 (0.60) | F2APLNRC5AR1EPHA2NTSR2 | |
| Trv-120027 SCHEMBL11023969 | 0.85 | AGTR1 (0.60) | F2APLNRC5AR1EPHA2NTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169291-B2 | Covalent conjugates between endoperoxides and transferrin and lactoferrin receptor-binding agents | UNIVERSITY OF WASHINGTON (US) | 2015-10-27 | — | — | US | disclosed |
| US-20110150830-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | WASHINGTON, UNIVERSITY OF (US) | 2011-06-23 | — | — | US | disclosed |
| US-20070231300-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | WASHINGTON, UNIVERSITY OF (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2007112451-A2 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | UNIVERSITY OF WASHINGTON (US) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150830-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | TFRC, LPO, FTH1 | CTSL 497/4885CTSS 456/4885CTSK 851/4885 |
| US-20070231300-A1 | COVALENT CONJUGATES BETWEEN ENDOPEROXIDES AND TRANSFERRIN AND LACTOFERRIN RECEPTOR-BINDING AGENTS | TFRC, LPO, FTH1 | CTSL 497/4885CTSS 456/4885CTSK 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.