Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6012235 | 0.84 | BDKRB2 (0.40) | NEK2CXCR3 | |
| SCHEMBL30415331 | 0.78 | HSD17B10 (0.41) | HSD17B10NEK2 | |
| SCHEMBL6012396 | 0.76 | DRD2 (0.44) | CXCR3 | |
| SCHEMBL17128982 | 0.74 | MEN1 (0.45) | HSD17B10POLBL3MBTL1 | |
| SCHEMBL5562519 | 0.74 | SLC6A9 (0.48) | HSD17B10HTR2AHTR2C | |
| SCHEMBL6012726 | 0.74 | CXCR3 (0.59) | CXCR3 | |
| SCHEMBL6611036 | 0.73 | CCR5 (0.52) | CXCR3 | |
| SCHEMBL6614177 | 0.71 | CCR5 (0.57) | CXCR3 | |
| SCHEMBL8363874 | 0.71 | HTR2A (0.33) | NEK2HTR2AHTR2C | |
| SCHEMBL2452166 | 0.71 | SMN1; SMN2 (0.36) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285875-B | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |