Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Fosfocreatine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfocreatine SCHEMBL612834 | 0.96 | — | — | |
| Fosfocreatine SCHEMBL9319928 | 0.96 | — | — | |
| Fosfocreatine SCHEMBL30173229 | 0.84 | — | — | |
| Fosfocreatine SCHEMBL1640494 | 0.82 | MVD (0.38) | — | |
| Fosfocreatine SCHEMBL30031412 | 0.82 | MVD (0.38) | — | |
| Fosfocreatine SCHEMBL30930087 | 0.81 | MVD (0.37) | — | |
| Fosfocreatine SCHEMBL31181876 | 0.81 | MVD (0.37) | — | |
| Creatine SCHEMBL9568829 | 0.74 | NOS3 (0.39) | — | |
| Creatine SCHEMBL1065566 | 0.70 | NOS3 (0.39) | — | |
| Creatine SCHEMBL939498 | 0.69 | CA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334095-B2 | Compositions and methods for monosynaptic transport | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-12-18 | — | — | US | disclosed |
| US-20100304364-A1 | Compositions and methods for monosynaptic transport | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2010-12-02 | — | — | US | disclosed |
| US-7785874-B2 | Compositions and methods for monosynaptic transport | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080193918-A1 | Compositions and methods for monosynaptic transport | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2008-08-14 | — | — | US | disclosed |