SCHEMBL3028363

SCHEMBL3028363

CC(=O)c1ccc(C=Cc2cc(C(C)=O)cc(C(C)=O)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.47
▸ PTGS2 P35354 1/20 0.47
▸ MAOB P27338 1/20 0.47
▸ ADORA2A P29274 1/20 0.47
▸ LMNA P02545 3/20 0.46
▸ MAPT P10636 5/20 0.46
▸ KMT2A Q03164 4/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ TTR P02766 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ TP53 P04637 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ HPGD P15428 3/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ CYP19A1 P11511 1/20 0.42
▸ PTPN1 P18031 1/20 0.42
▸ HSD17B1 P14061 1/20 0.42
▸ CA5A P35218 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3028357 1.00 PTGS1 (0.47) PTGS1PTGS2MAOBADORA2ALMNA
SCHEMBL3641850 0.93 HSD17B1 (0.55) PTGS1PTGS2MAOBLMNAMAPT
SCHEMBL16687974 0.91 MAOB (0.49) MAOBADORA2ALMNAMAPTKMT2A
SCHEMBL8589165 0.89 LMNA (0.53) MAOBADORA2ALMNAMAPTKMT2A
SCHEMBL8589167 0.89 LMNA (0.53) MAOBADORA2ALMNAMAPTKMT2A
SCHEMBL3030012 0.88 TTR (0.55) PTGS1PTGS2MAOBLMNAMAPT
SCHEMBL3030016 0.88 TTR (0.55) PTGS1PTGS2MAOBLMNAMAPT
SCHEMBL18860733 0.84 PTGS1 (0.61) PTGS1PTGS2MAOBLMNAMAPT
SCHEMBL18860735 0.84 PTGS1 (0.61) PTGS1PTGS2MAOBLMNAMAPT
SCHEMBL6555140 0.81 LMNA (0.65) PTGS1PTGS2MAOBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2679243-B1 Co-precipitate of one or more stilbene polyphenols in lamellar anionic solids, it's applications and related preparation method FIORETTI BERNARD (IT) 2017-05-24 — — EP claimed
US-8912234-B2 Composition containing resveratrol and/or derivatives thereof and plant oil, process for producing said composition, nutraceutical and/or pharmaceutical product, and method for enhancing the potential of resveratrol UNIAO Brasileria de Educacao e Assistencia—Mantenedora da PUCRS (BR) 2014-12-16 — — US claimed
US-20130040920-A1 COMPOSITION CONTAINING RESVERATROL AND/OR DERIVATIVES THEREOF AND PLANT OIL, PROCESS FOR PRODUCING SAID COMPOSITION, NUTRACEUTICAL AND/OR PHARMACEUTICAL PRODUCT, AND METHOD FOR ENHANCING THE POTENTIAL OF RESVERATROL UNIAO Brasileira de Educacao e Assistencia- Matenedora da PUCRS (BR) 2013-02-14 — — US claimed
US-20100204179-A1 Resveratrol complex and process for the preperation UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA - MANTENEDORA DA PUCRS (BR) 2010-08-12 — — US claimed
US-20230061229-A1 SMART WOUND DRESSINGS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2023-03-02 — — US disclosed
EP-2679243-B1 Co-precipitate of one or more stilbene polyphenols in lamellar anionic solids, it's applications and related preparation method FIORETTI BERNARD (IT) 2017-05-24 — — EP disclosed
US-8912234-B2 Composition containing resveratrol and/or derivatives thereof and plant oil, process for producing said composition, nutraceutical and/or pharmaceutical product, and method for enhancing the potential of resveratrol UNIAO Brasileria de Educacao e Assistencia—Mantenedora da PUCRS (BR) 2014-12-16 — — US disclosed
US-8476248-B2 Process for the preparation of a water-soluble complex having resveratrol compounds; products comprising said complex; and uses thereof Uniao Brasileira de Educacao e Assistencia—Mantenedora da PUCRS (BR) 2013-07-02 — — US disclosed
US-20130040920-A1 COMPOSITION CONTAINING RESVERATROL AND/OR DERIVATIVES THEREOF AND PLANT OIL, PROCESS FOR PRODUCING SAID COMPOSITION, NUTRACEUTICAL AND/OR PHARMACEUTICAL PRODUCT, AND METHOD FOR ENHANCING THE POTENTIAL OF RESVERATROL UNIAO Brasileira de Educacao e Assistencia- Matenedora da PUCRS (BR) 2013-02-14 — — US disclosed
US-20100204179-A1 Resveratrol complex and process for the preperation UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA - MANTENEDORA DA PUCRS (BR) 2010-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130040920-A1 COMPOSITION CONTAINING RESVERATROL AND/OR DERIVATIVES THEREOF AND PLANT OIL, PROCESS FOR PRODUCING SAID COMPOSITION, NUTRACEUTICAL AND/OR PHARMACEUTICAL PRODUCT, AND METHOD FOR ENHANCING THE POTENTIAL OF RESVERATROL GPR119, MAVS, SIRT1 PTGS1 1237/4885PTGS2 1099/4885MAOB 1756/4885
US-20100204179-A1 Resveratrol complex and process for the preperation SI, GPR119, GYS1 PTGS1 1477/4885PTGS2 3134/4885MAOB 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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