Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP4 | P49662 | 1/20 | 0.30 |
| ▸ | CASP5 | P51878 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299398 | 0.94 | OPRM1 (0.34) | OPRM1OPRK1OPRL1CASP1CASP4 | |
| SCHEMBL30299303 | 0.86 | CYP17A1 (0.36) | OPRM1OPRK1OPRL1CASP1CASP4 | |
| SCHEMBL30299381 | 0.82 | IP6K1 (0.32) | — | |
| SCHEMBL29929683 | 0.81 | AXL (0.40) | — | |
| SCHEMBL30299388 | 0.80 | ROCK2 (0.34) | — | |
| SCHEMBL30299325 | 0.80 | ROCK2 (0.32) | — | |
| SCHEMBL30299377 | 0.80 | PDE3B (0.34) | PIM1 | |
| SCHEMBL29928123 | 0.80 | AXL (0.39) | — | |
| SCHEMBL30299298 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL30299337 | 0.79 | FPR1 (0.37) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |