Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.70 |
| ▸ | RELA | Q04206 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691483 | 0.85 | ALDH1A3 (0.62) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL13325728 | 0.84 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL1691698 | 0.81 | ALDH1A1 (0.52) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL13325718 | 0.81 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL5738428 | 0.81 | SMN1; SMN2 (0.70) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL5737395 | 0.80 | PPARG (0.61) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL10526803 | 0.78 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL13217828 | 0.77 | ALDH1A3 (0.75) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL13325729 | 0.74 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 | |
| SCHEMBL12848984 | 0.74 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752415-B1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECH ORGANISATION (AU) | 2017-10-11 | — | — | EP | disclosed |
| EP-2752415-A1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2014-07-09 | — | — | EP | disclosed |
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION | 2010-08-19 | — | — | US | disclosed |
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION | 2010-08-19 | — | — | US | disclosed |
| EP-2054060-A1 | FLUORINATED LIGANDS FOR TARGETING PERIPHERAL BENZODIAZEPINE RECEPTORS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008022396-A1 | FLUORINATED LIGANDS FOR TARGETING PERIPHERAL BENZODIAZEPINE RECEPTORS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | GABRA6, GABRA1, GABRA2 | NPC1 524/4885RAB9A 1716/4885SMN1; SMN2 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.