SCHEMBL30306602

SCHEMBL30306602

C=Cc1ccc(-c2ccc(C(=O)C(O)O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TSSK1B Q9BXA7 1/20 0.43
TAS1R3 Q7RTX0 3/20 0.42
TAS1R1 Q7RTX1 3/20 0.42
PDPK1 O15530 1/20 0.41
HDAC2 Q92769 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
PTGS2 P35354 3/20 0.37
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
BCL2L1 Q07817 1/20 0.32
BAD Q92934 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23419503 0.94 ALDH1A1 (0.50) ALDH1A1TSSK1BTAS1R3TAS1R1PDPK1
SCHEMBL1676005 0.79 ALDH1A1 (0.56) ALDH1A1HDAC2TDP1TSHRTP53
SCHEMBL10245562 0.79 ALDH1A1 (0.56) ALDH1A1HDAC2TDP1TSHRTP53
SCHEMBL10243239 0.78 CA12 (0.50) ALDH1A1HDAC2TDP1TSHRPOLB
SCHEMBL10247611 0.78 CA12 (0.50) ALDH1A1HDAC2TDP1TSHRPOLB
SCHEMBL9252175 0.78 TAS1R3 (0.51) ALDH1A1TAS1R3TAS1R1TDP1PTGS2
SCHEMBL4802353 0.78 HSD17B1 (0.57) ALDH1A1TAS1R3TAS1R1HDAC2TDP1
SCHEMBL1164038 0.77 SMN1; SMN2 (0.56) ALDH1A1TSSK1BLMNAHTTSMN1; SMN2
SCHEMBL6982065 0.77 ALDH1A1 (0.58) ALDH1A1PTGS2KMT2A
SCHEMBL3757038 0.76 CES2 (0.55) ALDH1A1TAS1R3TAS1R1TDP1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947711-B Photochemical caching agent and synthesis method thereof 上海泰辉生物科技有限公司 2024-06-11 CN disclosed
CN-115947711-A Photochemical buffering agent and synthesis method thereof 上海泰辉生物科技有限公司 2023-04-11 CN disclosed