SCHEMBL303160

SCHEMBL303160

c1ccc2c(c1)Cc1ccc3ccccc3c1O2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
HSD17B10 Q99714 3/20 0.40
CYP1A2 P05177 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2A6 P11509 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 1/20 0.36
KLK5 Q9Y337 1/20 0.36
HPRT1 P00492 1/20 0.35
ANPEP P15144 1/20 0.34
NFKB1 P19838 3/20 0.33
NFKB2 Q00653 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10378225 0.87 HSD17B10 (0.46) MAOAMAOBHSD17B10CYP1A2KDM4E
SCHEMBL30779751 0.87 HSD17B10 (0.46) MAOAMAOBHSD17B10CYP1A2KDM4E
SCHEMBL13777196 0.82 MAOA (0.73) MAOAMAOBCYP1A2KDM4EHPGD
SCHEMBL28394024 0.82 CYP2A6 (0.39) MAOAMAOBHSD17B10CYP1A2KDM4E
SCHEMBL28401274 0.82 MAOA (0.47) MAOAMAOBCYP1A2CYP2C9HPGD
SCHEMBL28888914 0.81 CYP1A2 (0.38) MAOAMAOBHSD17B10CYP1A2KDM4E
SCHEMBL28405398 0.81 NFKB1 (0.40) MAOAMAOBHSD17B10CYP1A2KDM4E
SCHEMBL10378227 0.81 KDM4E (0.54) HSD17B10CYP1A2KDM4EGLACYP2C9
SCHEMBL5657956 0.79 CYP19A1 (0.47) MAOAMAOBHSD17B10CYP1A2KDM4E
SCHEMBL4015217 0.79 AKR1B1 (0.37) MAOAMAOBHSD17B10CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397718-A1 FLUORESCENT PARTICULATE MATERIAL L'Oréal (FR) 2018-11-07 EP claimed
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO claimed
US-9040307-B2 Fluorescent pH detector system and related methods BLOOD CELL STORAGE, INC. (US) 2015-05-26 US claimed
EP-1781675-B1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES INC (US) 2014-03-26 EP claimed
US-20120322161-A1 FLUORESCENT pH DETECTOR SYSTEM AND RELATED METHODS BLOOD CELL STORAGE, INC. (US) 2012-12-20 US claimed
JP-2012500860-A 2012-01-12 JP claimed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 US claimed
WO-2010021512-A2 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 WO claimed
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 US claimed
EP-2049601-B1 NOVEL POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (POSS) BASED FLUORESCENT COLORANTS BASF SE (DE) 2009-12-09 EP claimed
US-20050277144-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-12-15 US claimed
US-20050176066-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-08-11 US claimed
US-20050171340-A1 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2005-08-04 US claimed
US-20050159606-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-07-21 US claimed
WO-2005040357-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2005-05-06 WO claimed
EP-1466176-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING Epoch Biosciences, Inc. (US) 2004-10-13 EP claimed
US-20030152518-A1 Detection by increased uptake of fluorophore glucose or deoxyglucose conjugates in cancerous and pre-cancerous cells relative to normal cells. THRESHOLD PHARMACEUTICALS, INC. 2003-08-14 US claimed
WO-2003059149-A2 METHODS FOR CANCER IMAGING THRESHOLD PHARMACEUTICALS, INC. (US) 2003-07-24 WO claimed
WO-2003023357-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2003-03-20 WO claimed
US-4945171-A FLUORESCENT DYES MOLECULAR PROBES, INC. (US) 1990-07-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030152518-A1 Detection by increased uptake of fluorophore glucose or deoxyglucose conjugates in cancerous and pre-cancerous cells relative to normal cells. SLC2A1, SLC2A4, SLC2A8 MAOA 3763/4885MAOB 3603/4885HSD17B10 2478/4885
US-20050176066-A1 Compounds and methods for fluorescent labeling HLCS, GLB1, TUBB MAOA 1107/4885MAOB 313/4885HSD17B10 2560/4885
US-20050171340-A1 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING HLCS, GLB1, TUBB MAOA 1107/4885MAOB 313/4885HSD17B10 2560/4885
US-20050277144-A1 Compounds and methods for fluorescent labeling HLCS, GLB1, TUBB MAOA 1107/4885MAOB 313/4885HSD17B10 2560/4885
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES NOXO1, NOX3, SOS1 MAOA 3726/4885MAOB 4043/4885HSD17B10 2638/4885
US-20050159606-A1 Compounds and methods for fluorescent labeling TFEB, HLCS, PFAS MAOA 863/4885MAOB 211/4885HSD17B10 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.