Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 17/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 16/20 | 1.00 |
| ▸ | GSK3A | P49840 | 15/20 | 1.00 |
| ▸ | CDK1 | P06493 | 14/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 6/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 5/20 | 1.00 |
| ▸ | AURKC | Q9UQB9 | 5/20 | 1.00 |
| ▸ | AURKA | O14965 | 3/20 | 1.00 |
| ▸ | AHR | P35869 | 1/20 | 1.00 |
| ▸ | DYRK2 | Q92630 | 1/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.70 |
| ▸ | CCNB2 | O95067 | 11/20 | 0.70 |
| ▸ | CCNB3 | Q8WWL7 | 11/20 | 0.70 |
| ▸ | FLT3 | P36888 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indirubin-3-Monoxime SCHEMBL29354191 | 0.83 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30319828 | 0.79 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL29361130 | 0.78 | GSK3B (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL31307772 | 0.75 | GSK3B (0.75) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL29484209 | 0.74 | GSK3B (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30319818 | 0.74 | GSK3B (0.83) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL29924508 | 0.71 | GSK3B (0.72) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30141665 | 0.71 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30309734 | 0.70 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30655964 | 0.68 | KIF11 (0.59) | GSK3BCDK5R1CDK5GSK3ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240358678-A1 | METHODS AND COMPOSITIONS FOR ENHANCING CHEMOTHERAPEUTIC DRUG UPTAKE INTO BRAIN TUMORS | BROWN UNIVERSITY | 2024-10-31 | — | — | US | disclosed |
| US-20230122229-A1 | USE OF PULSED FOCUSED ULTRASOUND THERAPY IN COMBINATION WITH MESENCHYMAL STROMAL CELLS OR MESENCHYMAL STROMAL CELL-DERIVED EXTRACELLULAR VESICLES FOR REGENERATION OF KIDNEY TISSUE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240358678-A1 | METHODS AND COMPOSITIONS FOR ENHANCING CHEMOTHERAPEUTIC DRUG UPTAKE INTO BRAIN TUMORS | SLC19A1, SLC5A7, FABP7 | GSK3B 1329/4885CDK5R1 1679/4885CDK5 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.