Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 15/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 15/20 | 1.00 |
| ▸ | CDK1 | P06493 | 14/20 | 1.00 |
| ▸ | GSK3A | P49840 | 13/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 13/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 12/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 12/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | THPO | P40225 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319828 | 0.91 | CDK5R1 (1.00) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| Indirubin-3-Monoxime SCHEMBL29354191 | 0.88 | CDK5R1 (1.00) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL30278941 | 0.78 | GSK3B (1.00) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL29484209 | 0.78 | GSK3B (1.00) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL30319818 | 0.78 | GSK3B (0.83) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL30295559 | 0.77 | CDK1 (1.00) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL30141665 | 0.75 | CDK5R1 (1.00) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL29924508 | 0.74 | GSK3B (0.72) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL25294 | 0.70 | AHR (0.64) | GSK3BCDK5CDK5R1CDK1GSK3A | |
| SCHEMBL30286037 | 0.70 | AHR (0.64) | GSK3BCDK5CDK5R1CDK1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| US-12590297-B2 | Differentiation method | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2026-03-31 | — | — | US | claimed |
| US-20250304916-A1 | METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS | TRAILHEAD BIOSYSTEMS INC (US) | 2025-10-02 | — | — | US | claimed |
| EP-4594475-A1 | METHOD FOR MESENCHYMAL PHENOTYPE REVERSION IN PRIMARY HUMAN CORNEAL ENDOTHELIAL CELLS | Università degli Studi di Modena e Reggio Emilia (IT) | 2025-08-06 | — | — | EP | claimed |
| CN-119698462-A | Two-dimensional culture method with definite chemical composition for culturing three-dimensional intestinal organoid derived intestinal stem cell population | 韩国生命工学研究院 | 2025-03-25 | — | — | CN | claimed |
| CN-113631701-B | Choroid plexus organ and method for producing same | 英国研究与创新组织 | 2025-03-14 | — | — | CN | claimed |
| US-12209255-B2 | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof | ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) | 2025-01-28 | — | — | US | claimed |
| EP-4466342-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | Institut Pasteur (FR) | 2024-11-27 | — | — | EP | claimed |
| CN-118497113-A | Culture medium and method for preparing cell culture meat based on pluripotent stem cells | 上海遇见味来生物技术有限公司 | 2024-08-16 | — | — | CN | claimed |
| US-20240148835-A1 | TREATING DISORDERS ASSOCIATED WITH DYRK1A DYSFUNCTION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-05-09 | — | — | US | claimed |
| CN-115666520-A | Hydrogel drug delivery compositions | 内布拉斯加大学董事会 | 2023-01-31 | — | — | CN | claimed |
| CN-109562140-B | Combination therapy for inner ear sensory hair cell regeneration/replacement | 霍夫耳科研究所 | 2023-01-03 | — | — | CN | claimed |
| WO-2022229985-A1 | SOLUBLE ANALOGUES OF 6BIO THEREOF AND IMPLEMENTATION THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2022-11-03 | — | — | WO | claimed |
| CN-115161257-A | Improved differentiation process | 荷兰皇家科学院 | 2022-10-11 | — | — | CN | claimed |
| CN-108291197-B | Method for generating sensory epithelium and sensory neurons of human inner ear | 印第安纳大学研究与技术公司 | 2022-09-16 | — | — | CN | claimed |
| EP-4045666-A1 | COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS | Orchard Therapeutics (Europe) Limited (GB) | 2022-08-24 | — | — | EP | claimed |
| WO-2022165250-A1 | TREATING DISORDERS ASSOCIATED WITH DYRK1A DYSFUNCTION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-08-04 | — | — | WO | claimed |
| WO-2022110494-A1 | METHOD FOR REPROGRAMMING CELL | 北京赛尔湃腾科技咨询合伙企业(有限合伙) | 2022-06-02 | — | — | WO | claimed |
| CN-109477070-B | Improved differentiation process | 荷兰皇家科学院 | 2022-05-27 | — | — | CN | claimed |
| EP-3982929-A1 | HYDROGEL DRUG DELIVERY COMPOSITION | Board of Regents of the University of Nebraska (US) | 2022-04-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | WNT3A, GSK3B, GSK3A | GSK3B 2/4885CDK5 919/4885CDK5R1 935/4885 |
| US-12590297-B2 | Differentiation method | WNT3A, SFRP1, WNT1 | GSK3B 7/4885CDK5 1508/4885CDK5R1 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.