Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034996 | 0.83 | PGR (0.40) | — | |
| SCHEMBL15273880 | 0.79 | CACNA1B (0.33) | KDM4E | |
| SCHEMBL3018579 | 0.79 | HTR1A (0.32) | — | |
| SCHEMBL869025 | 0.78 | PGR (0.39) | PDE3BPDE3ANOTUMCYP1A2AR | |
| SCHEMBL3034438 | 0.78 | L3MBTL1 (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL3036676 | 0.78 | HTR1A (0.32) | — | |
| SCHEMBL868403 | 0.78 | MARS1 (0.36) | SMN1; SMN2 | |
| SCHEMBL3031120 | 0.77 | NOTUM (0.30) | NOTUM | |
| SCHEMBL12128943 | 0.77 | COMT (0.38) | PDE3BPDE3ANOTUMCYP1A2AR | |
| SCHEMBL15273966 | 0.77 | DGAT1 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006429-B2 | Herbicidal pyrandione, thiopyrandione, and cyclohexanetrione derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2102181-B1 | 4-PHENYL-PYRANE-3,5-DIONES, 4-PHENYL-THIOPYRANE-3,5-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-18 | — | — | EP | disclosed |
| US-8680012-B2 | 4-phenyl-pyrane-3,5-diones,4-phenyl-thiopyrane-3,6-diones and cyclohexanetriones as novel herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-03-25 | — | — | US | disclosed |
| US-20140005389-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2014-01-02 | — | — | US | disclosed |
| US-20100210466-A1 | 4-PHENYL-PYRANE-3,5-DIONES,4-PHENYL-THIOPYRANE-3,6-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-08-19 | — | — | US | disclosed |
| EP-2102181-A1 | 4-PHENYL-PYRANE-3,5-DIONES, 4-PHENYL-THIOPYRANE-3,5-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES | Syngeta Participations AG (CH) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008071405-A1 | 4-PHENYL-PYRANE-3,5-DIONES, 4-PHENYL-THIOPYRANE-3,5-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210466-A1 | 4-PHENYL-PYRANE-3,5-DIONES,4-PHENYL-THIOPYRANE-3,6-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES | DDT, HPD, CYP4B1 | PDE3B 2877/4885PDE3A 1648/4885NOTUM 402/4885 |
| US-20140005389-A1 | NOVEL HERBICIDES | DDT, HPD, HCAR3 | PDE3B 3699/4885PDE3A 3066/4885NOTUM 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.