SCHEMBL304757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL303366	0.95	L3MBTL1 (0.56)	L3MBTL1PTGESALOX5NPSR1KEAP1
	SCHEMBL301844	0.87	KEAP1 (0.49)	L3MBTL1PTGESALOX5NPSR1KEAP1
	SCHEMBL303525	0.86	KMT2A (0.53)	L3MBTL1MAPTPOLBTSHRPKM
	SCHEMBL3377911	0.86	MAPT (0.54)	L3MBTL1PTGESMAPTGAAHTT
	SCHEMBL3380874	0.85	NR3C1 (0.54)	PTGESKEAP1NFE2L2MAPTGAA
	SCHEMBL303293	0.81	GAA (0.63)	MAPTGAAHTT
	SCHEMBL302950	0.81	NR3C1 (0.55)	PTGESKEAP1NFE2L2MAPTPOLB
	SCHEMBL3380436	0.80	NR1H2 (0.45)	ALDH1A1MAPTTP53MCL1
	SCHEMBL301986	0.80	NAMPT (0.51)	NPSR1KEAP1NFE2L2ALDH1A1MAPT
	SCHEMBL3376229	0.80	ALDH1A1 (0.53)	L3MBTL1PTGESALOX5NPSR1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.