Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917482 | 0.76 | CYP19A1 (1.00) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6003706 | 0.75 | ALDH1A1 (0.57) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL9382670 | 0.74 | CYP19A1 (0.96) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL1563130 | 0.74 | TSHR (0.48) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3235402 | 0.73 | NPC1 (0.72) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7138301 | 0.73 | CYP19A1 (0.67) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3484265 | 0.72 | HMOX1 (0.48) | TP53TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10701931 | 0.71 | CYP19A1 (0.50) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6648239 | 0.70 | CYP19A1 (0.62) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9023539 | 0.70 | CYP19A1 (0.86) | CYP19A1SMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035357-C | Pharmaceutical preparations | MACK CHEM PHARM (DE) | 1997-07-09 | — | — | CN | claimed |
| CN-1052046-A | pharmaceutical preparation | MACK CHEM PHARM (DE) | 1991-06-12 | — | — | CN | claimed |
| CN-110603032-A | Strippable nail paint | 牡蛎壳公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-110582261-A | Colored cuticle separating nail lacquer | 牡蛎壳公司 | 2019-12-17 | — | — | CN | disclosed |
| EP-2210880-B1 | Benzoxazinone derivatives | MSD KK (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8314094-B2 | Benzoxazinone derivative | MSD K.K (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20100210636-A1 | BENZOXAZINONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2010-08-19 | — | — | US | disclosed |
| EP-2210880-A1 | BENZOXAZINONE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-07-28 | — | — | EP | disclosed |
| EP-1827400-A2 | TOPICAL SKIN PATCH CONTAINING XANTHOPHYLLS | Nu-Tein Co., Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006062740-A2 | TOPICAL SKIN PATCH CONTAINING XANTHOPHYLLS | NU-TEIN CO., INC. (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060122282-A1 | METHOD FOR TREATING SKIN DISORDERS WITH XANTHOPHYLLS | NU-TEIN CO., INC. | 2006-06-08 | — | — | US | disclosed |
| CN-1035357-C | Pharmaceutical preparations | MACK CHEM PHARM (DE) | 1997-07-09 | — | — | CN | disclosed |
| CN-1052046-A | pharmaceutical preparation | MACK CHEM PHARM (DE) | 1991-06-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210636-A1 | BENZOXAZINONE DERIVATIVE | HAX1, CYP4X1, CYP19A1 | CYP19A1 3/4885SMN1; SMN2 1730/4885NPC1 2353/4885 |
| US-20060122282-A1 | METHOD FOR TREATING SKIN DISORDERS WITH XANTHOPHYLLS | COL1A1, COL2A1, KRT18 | CYP19A1 785/4885SMN1; SMN2 4229/4885NPC1 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.