SCHEMBL30376277

SCHEMBL30376277

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ NPBWR1 P48145 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31256796 0.92 NPBWR1 (0.59) NPBWR1
SCHEMBL31257043 0.91 OPRM1 (0.56) NPBWR1
SCHEMBL18862075 0.90 NPBWR1 (0.60) NPBWR1
SCHEMBL30219058 0.89 ERAP2 (0.60) NPBWR1
SCHEMBL18854324 0.88 ERAP2 (0.58) NPBWR1
SCHEMBL30199174 0.88 NPBWR1 (0.57) NPBWR1
SCHEMBL30169836 0.86 ERAP2 (0.63) NPBWR1
SCHEMBL29376430 0.86 OPRM1 (0.61) NPBWR1
SCHEMBL29589496 0.86 GHSR (0.54) —
SCHEMBL5271284 0.86 GHSR (0.55) NPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190938-A1 GIP DERIVATIVES AND USES THEREOF NOVO NORDISK AS (DK) 2024-06-13 — — US disclosed
US-11633459-B2 GIP derivatives and uses thereof NOVO NORDISK A/S (DK) 2023-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633459-B2 GIP derivatives and uses thereof GIPR, GLP1R, GPR119 NPBWR1 21/4885
US-20240190938-A1 GIP DERIVATIVES AND USES THEREOF GIPR, GLP1R, GPR119 NPBWR1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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