Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912380 | 0.84 | TBXAS1 (0.69) | TBXAS1CYP1A2CYP2C9MAPK1HIF1A | |
| SCHEMBL3047178 | 0.82 | XIAP (0.46) | TBXAS1MAPK1S100A4PTPN1ALDH1A1 | |
| SCHEMBL15698057 | 0.81 | TBXAS1 (0.45) | TBXAS1CYP1A2CYP2C9MAPK1HIF1A | |
| SCHEMBL5710686 | 0.81 | TRAP1 (0.51) | TBXAS1CYP1A2CYP2C9MAPK1HIF1A | |
| SCHEMBL29747247 | 0.78 | TBXAS1 (0.75) | TBXAS1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL15698056 | 0.78 | TBXAS1 (0.47) | TBXAS1CYP1A2CYP2C9MAPK1HIF1A | |
| SCHEMBL2715544 | 0.78 | TBXAS1 (0.75) | TBXAS1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL756070 | 0.77 | MAPK1 (0.44) | TBXAS1CYP1A2CYP2C9MAPK1HIF1A | |
| SCHEMBL5732104 | 0.77 | FFAR1 (0.49) | TBXAS1LMNAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL594558 | 0.77 | TBXAS1 (0.73) | TBXAS1CYP1A2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024085-A1 | ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | PTC THERAPEUTICS, INC. | 2016-01-28 | — | — | US | disclosed |
| WO-2010005989-A1 | DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES | EDISON PHARMACEUTICALS, INC. (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20100010100-A1 | DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES | EDISON PHARMACEUTICALS, INC. | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024085-A1 | ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | NQO1, COQ8A, NDUFAB1 | TBXAS1 826/4885CYP1A2 1279/4885CYP2C9 3690/4885 |
| US-20100010100-A1 | DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES | TYR, TELO2, LPO | TBXAS1 1725/4885CYP1A2 3058/4885CYP2C9 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.