SCHEMBL756070

SCHEMBL756070

CC1=CC(=O)C(C)=C(Cc2ccccc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
HIF1A Q16665 2/20 0.44
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
MEN1 O00255 2/20 0.44
USP2 O75604 2/20 0.44
GAA P10253 2/20 0.44
BLM P54132 2/20 0.44
KMT2A Q03164 2/20 0.44
PLIN1 O60240 1/20 0.44
NR1I2 O75469 1/20 0.44
GSR P00390 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ADORA3 P0DMS8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27513629 0.84 XIAP (0.49) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL3040732 0.77 TBXAS1 (0.50) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL16817137 0.76 MAOA (0.48) MAPK1LMNACYP1A2CYP2C9HIF1A
SCHEMBL7912380 0.74 TBXAS1 (0.69) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL11790353 0.72 XIAP (0.41) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL5710686 0.71 TRAP1 (0.51) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL15698057 0.71 TBXAS1 (0.45) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL15698056 0.69 TBXAS1 (0.47) MAPK1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL8138381 0.68 MEN1 (0.34) MAPK1ALDH1A1LMNAMAPTCYP1A2
SCHEMBL27623517 0.68 MAOA (0.57) MAPK1LMNACYP1A2CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419580-B1 METHOD FOR PROMOTING HYDROSILYLATION REACTION TO PREPARE ESTER-FUNCTIONAL SILOXANE OLIGOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-27 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions DOW SILICONES CORPORATION (US) 2025-08-05 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
EP-4172165-B1 PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS DOW SILICONES CORP (US) 2025-07-23 EP disclosed
US-20250136625-A1 PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS BASF SE (DE) 2025-05-01 US disclosed
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS DOW SILICONES CORP (US) 2025-05-01 US disclosed
EP-4508106-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
EP-4508054-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH VINYLESTER FUNCTIONALITY Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
US-12215117-B2 Method of preparing acryloxy-functional organosilicon compounds DOW SILICONES CORPORATION (US) 2025-02-04 US disclosed
WO-2004087635-A2 MIXTURES OF COMPOUNDS COMPRISING AT LEAST TWO DOUBLE BONDS AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2004-10-14 WO disclosed
US-20040050679-A1 Method for producing (meth) acrylic acid BASF AKTIENGESELLSCHAFT (DE) 2004-03-18 US disclosed
US-20040031674-A1 Workup of (meth)acrylic acid and (meth)acrylic esters BASF AKIENGESELLSCHAFT (DE) 2004-02-19 US disclosed
WO-2003104302-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED TRIMETHYLOLPROPANE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104300-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED TRIMETHYLOLPROPANE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104301-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED GLYCERINE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003099757-A1 STABILISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS COMPRISING HYDROXYLAMINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2003-12-04 WO disclosed
EP-1345882-A2 METHOD FOR PRODUCING (METH)ACRYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2003-09-24 EP disclosed
US-20030060654-A1 Preparation of polymerizable compounds BASF AKIENGESELLSCHAFT (DE) 2003-03-27 US disclosed
WO-2002051786-A2 METHOD FOR PRODUCING (METH)ACRYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2002-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions MSR1, OXSR1, RIOX2 MAPK1 4154/4885ALDH1A1 1749/4885LMNA 458/4885
US-12215117-B2 Method of preparing acryloxy-functional organosilicon compounds MSMO1, ADH5, ADH1C MAPK1 3178/4885ALDH1A1 117/4885LMNA 3316/4885
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS VCL, FANCF, MMS19 MAPK1 3155/4885ALDH1A1 592/4885LMNA 570/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 MAPK1 2388/4885ALDH1A1 2965/4885LMNA 3227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.