Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206991 | 0.98 | GAA (0.35) | GAAHPGDL3MBTL1L3MBTL3CA12 | |
| SCHEMBL15941744 | 0.96 | MEN1 (0.35) | GAAHPGDL3MBTL1L3MBTL3CA12 | |
| SCHEMBL30425911 | 0.87 | L3MBTL3 (0.35) | HPGDL3MBTL1L3MBTL3MEN1KMT2A | |
| SCHEMBL2552216 | 0.85 | HTR6 (0.39) | GAAHPGDL3MBTL1L3MBTL3CA12 | |
| SCHEMBL29360628 | 0.85 | ALDH1A1 (0.39) | HPGDL3MBTL1L3MBTL3MEN1KMT2A | |
| SCHEMBL28287138 | 0.85 | ALDH1A1 (0.38) | GAAHPGDL3MBTL1L3MBTL3SIGMAR1 | |
| SCHEMBL3237715 | 0.81 | HSD11B1 (0.45) | SIGMAR1 | |
| SCHEMBL2245558 | 0.79 | HPGD (0.34) | GAAHPGDL3MBTL1L3MBTL3CA12 | |
| SCHEMBL3429553 | 0.79 | GAA (0.34) | GAAHPGDL3MBTL1L3MBTL3CA12 | |
| SCHEMBL30938358 | 0.79 | CHRNB2 (0.37) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182308-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | claimed |