Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005965 | 0.84 | CYP19A1 (0.35) | CYP19A1SIGMAR1TSHRL3MBTL1KDM4E | |
| SCHEMBL9201461 | 0.78 | SIGMAR1 (0.46) | CYP19A1SIGMAR1L3MBTL1KDM4EF2 | |
| SCHEMBL30790620 | 0.73 | HTR7 (0.39) | KDM4ECYP11B1CYP11B2CYP1A2MAPT | |
| SCHEMBL8672368 | 0.68 | SIGMAR1 (0.41) | CYP19A1SIGMAR1L3MBTL1KDM4EF2 | |
| SCHEMBL24938710 | 0.67 | MGLL (0.45) | CYP19A1SIGMAR1L3MBTL1KDM4EF2 | |
| SCHEMBL5011455 | 0.66 | CALM1 (0.34) | CYP19A1SIGMAR1TSHRKDM4ENPSR1 | |
| SCHEMBL6705444 | 0.66 | SIGMAR1 (0.48) | CYP19A1SIGMAR1F2PLGELANE | |
| Hydrochloric Acid SCHEMBL28835985 | 0.66 | MGLL (0.43) | CYP19A1SIGMAR1L3MBTL1KDM4EF2 | |
| SCHEMBL21104726 | 0.66 | SIGMAR1 (0.43) | CYP19A1SIGMAR1TSHRF2PLG | |
| SCHEMBL6615669 | 0.66 | GSK3A (0.36) | CYP19A1SIGMAR1TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143804-B | Tetracyclic quinolone compound, pharmaceutically acceptable salt and application thereof | 核新生物医药(长春)有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-116143804-A | Tetracyclic quinolone compound, pharmaceutically acceptable salt and application thereof | 核新生物医药(长春)有限公司 | 2023-05-23 | — | — | CN | disclosed |