SCHEMBL304773

SCHEMBL304773

COC(=O)N(C(C)C)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 2/20 0.37
BCHE P06276 1/20 0.37
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CA12 O43570 1/20 0.34
KCNA5 P22460 3/20 0.33
POLB P06746 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20780290 0.81 MMP1 (0.32) CA14KCNA5
SCHEMBL11344592 0.74 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL12988855 0.74 TSHR (0.46) CA14BCHEALDH1A1CA12HCAR2
SCHEMBL304772 0.74 BCHE (0.33) BCHE
SCHEMBL3636117 0.74
SCHEMBL25477680 0.74 BCHE (0.33) BCHE
SCHEMBL16965826 0.74 TSHR (0.33) BCHE
SCHEMBL3526460 0.74 BCHE (0.36) BCHEALDH1A1
SCHEMBL5921933 0.74
SCHEMBL8985024 0.74 BCHE (0.33) BCHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687490-B2 2-thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2010-03-30 US claimed
EP-1870412-A1 2-THIOETHENYL CARBAPENEM DERIVATIVE MEIJI SEIKA KAISHA LTD. (JP) 2007-12-26 EP claimed
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2007-01-04 US claimed
US-12194020-B2 Reversing baldness through cannabinoid receptor activation POSTREL RICHARD (US) 2025-01-14 US disclosed
CN-114736219-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-114751920-B Antitumor compounds 法马马有限公司 2024-06-07 CN disclosed
CN-117865987-A Antitumor compounds 法马马有限公司 2024-04-12 CN disclosed
WO-2024073626-A2 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NUVATION BIO INC. (US) 2024-04-04 WO disclosed
US-11759444-B2 Methods for cancer and immunotherapy using prodrugs of glutamine analogs THE JOHNS HOPKINS UNIVERSITY (US) 2023-09-19 US disclosed
WO-2023125928-A1 MENIN INHIBITOR AND USE THEREOF 成都先导药物开发股份有限公司 2023-07-06 WO disclosed
US-20220249434-A1 Reversal of Baldness in Men and Women through Cannabinoid Receptor Activation POSTREL RICHARD (US) 2022-08-11 US disclosed
EP-1870412-A1 2-THIOETHENYL CARBAPENEM DERIVATIVE MEIJI SEIKA KAISHA LTD. (JP) 2007-12-26 EP disclosed
US-20070117839-A1 Two cyclic cinnamide compound EISAI R&D MANAGEMENT CO., LTD. 2007-05-24 US disclosed
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2007-01-04 US disclosed
US-20060160802-A1 Peptide deformylase inhibitors GLAXO GROUP LIMITED 2006-07-20 US disclosed
WO-2005005456-A2 PEPTIDE DEFORMYLASE INHIBITORS GLAXO GROUP LIMITED (GB) 2005-01-20 WO disclosed
CN-1127502-C Paroxetine methanesulfonate SMITHKLINE BEECHAM PLC (GB) 2003-11-12 CN disclosed
CN-1315949-A Salts of paroxetine SMITHKLINE BEECHAM PLC (GB) 2001-10-03 CN disclosed
US-5223633-A Deprotonating a carbamate; chelation with diamine; removal of protecting group BAYER AKTIENGESELLSCHAFT (DE) 1993-06-29 US disclosed
EP-0478076-A2 Processes for the preparation of hydroxyl-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11759444-B2 Methods for cancer and immunotherapy using prodrugs of glutamine analogs ADORA2A, ADORA1, ADORA2B CA14 2921/4885BCHE 1425/4885ALDH1A1 342/4885
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MTAP, BLVRB, BPGM CA14 2099/4885BCHE 25/4885ALDH1A1 1182/4885
US-20070117839-A1 Two cyclic cinnamide compound APP, BACE1, PSEN1 CA14 4499/4885BCHE 526/4885ALDH1A1 869/4885
US-20060160802-A1 Peptide deformylase inhibitors PDF, PEPD, DPEP1 CA14 4836/4885BCHE 3091/4885ALDH1A1 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.