Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1S | Q13698 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691585 | 0.85 | LMNA (0.49) | KMT2ATSHRPYGLPYGMMEN1 | |
| SCHEMBL10695532 | 0.85 | TSHR (0.65) | KMT2ATSHRPYGLPYGMCYP19A1 | |
| SCHEMBL30489285 | 0.85 | TSHR (0.65) | KMT2ATSHRPYGLPYGMCYP19A1 | |
| SCHEMBL6281661 | 0.79 | CACNA1S (0.53) | CACNA1SCYP19A1 | |
| SCHEMBL10691415 | 0.78 | DRD2 (0.44) | KMT2AMEN1CYP19A1 | |
| SCHEMBL6275952 | 0.77 | F10 (0.67) | CACNA1S | |
| SCHEMBL9148955 | 0.74 | CYP19A1 (0.59) | TSHRCYP19A1 | |
| SCHEMBL23959055 | 0.72 | RAB9A (0.51) | CACNA1S | |
| SCHEMBL10688450 | 0.71 | ADRA1A (0.46) | KMT2ATSHRPYGLPYGM | |
| SCHEMBL9560256 | 0.71 | MAPT (0.56) | KMT2APYGLPYGMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0212216-A1 | Dihydroquinolinone derivatives, processes for their preparation, medicaments containing them, the use of these medicaments, and intermediates for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |