SCHEMBL30499616

SCHEMBL30499616

CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 7/20 0.66
▸ AGTR2 P50052 2/20 0.59
▸ AGTR1 P30556 1/20 0.59
▸ NTSR1 P30989 2/20 0.59
▸ NTSR2 O95665 1/20 0.58
▸ OPRM1 P35372 1/20 0.58
▸ NMUR2 Q9GZQ4 1/20 0.58
▸ KEAP1 Q14145 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30876339 0.92 OPRD1 (0.58) OPRD1OPRM1NMUR2KEAP1
SCHEMBL29386868 0.84 OPRD1 (0.82) OPRD1NTSR1OPRM1
SCHEMBL31332244 0.84 CXCL8 (0.64) —
SCHEMBL29462878 0.83 OPRK1 (0.54) OPRD1OPRM1
SCHEMBL31501224 0.83 OPRK1 (0.54) OPRD1OPRM1
Analog Of Dynorphin A SCHEMBL29389694 0.83 OPRD1 (0.86) OPRD1NTSR1NTSR2OPRM1
Dynorphin A (1-11) SCHEMBL30132402 0.83 OPRD1 (0.86) OPRD1NTSR1NTSR2OPRM1
SCHEMBL31332122 0.82 CALCR (0.64) OPRD1NTSR1OPRM1
SCHEMBL29878209 0.82 OPRD1 (0.85) OPRD1NTSR1NTSR2OPRM1
SCHEMBL1062481 0.82 OPRK1 (0.56) OPRD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 — — CN claimed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 — — US disclosed
EP-4596689-A1 ENZYME AGENT AND USE THEREOF Amano Enzyme Inc. (JP) 2025-08-06 — — EP disclosed
CN-120092086-A Enzyme agent and application thereof 天野酶制品株式会社 2025-06-03 — — CN disclosed
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 — — CN disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
WO-2024071388-A1 ENZYME AGENT AND USE THEREOF 天野エンザイム株式会社 2024-04-04 — — WO disclosed
US-20230201353-A1 SUSTAINED RELEASE DELIVERY SYSTEMS COMPRISING TRACELESS LINKERS NOVARTIS AG (CH) 2023-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230201353-A1 SUSTAINED RELEASE DELIVERY SYSTEMS COMPRISING TRACELESS LINKERS ABCB11, ABCB1, GHRHR OPRD1 3378/4885AGTR2 930/4885AGTR1 653/4885
US-12433949-B2 Sustained release delivery systems comprising traceless linkers ABCB11, ABCB1, GHRHR OPRD1 3378/4885AGTR2 930/4885AGTR1 653/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR OPRD1 501/4885AGTR2 100/4885AGTR1 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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