Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535671 | 0.86 | F2RL1 (0.46) | CYP4F2CYP4A11DRD2LMNAMAPT | |
| SCHEMBL305427 | 0.84 | TDP1 (0.50) | LMNAMAPTL3MBTL1TDP1 | |
| SCHEMBL2890795 | 0.83 | FFAR1 (0.47) | CYP4F2CYP4A11DRD2TDP1 | |
| SCHEMBL4000606 | 0.82 | LMNA (0.48) | DRD2LMNAMAPTL3MBTL1PREP | |
| SCHEMBL4266308 | 0.82 | FFAR1 (0.53) | LMNAL3MBTL1 | |
| SCHEMBL4261600 | 0.81 | PREP (0.42) | LMNAL3MBTL1PREP | |
| SCHEMBL7254705 | 0.81 | DRD2 (0.74) | CYP4F2CYP4A11DRD2LMNAPDE3B | |
| SCHEMBL68902 | 0.80 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1LMNAMAPT | |
| SCHEMBL9138459 | 0.78 | CYP4Z1 (0.46) | CYP4F2CYP4A11DRD2CYP4Z1TDP1 | |
| SCHEMBL1741166 | 0.78 | THRB (0.42) | DRD2LMNAL3MBTL1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12251370-B2 | Small molecule inhibitors of the BfrB:Bfd interaction | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2025-03-18 | — | — | US | disclosed |
| US-20220031661-A1 | SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION | UNIVERSITY OF KANSAS | 2022-02-03 | — | — | US | disclosed |
| US-20220031661-A1 | SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION | UNIVERSITY OF KANSAS | 2022-02-03 | — | — | US | disclosed |
| WO-2020117832-A1 | SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION | UNIVERSITY OF KANSAS (US) | 2020-06-11 | — | — | WO | disclosed |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20120071457-A1 | METALLO-BETA-LACTAMASE INHIBITORS | CHIKAUCHI KEN (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120071457-A1 | METALLO-BETA-LACTAMASE INHIBITORS | CHIKAUCHI KEN (JP) | 2012-03-22 | — | — | US | disclosed |
| US-8093294-B2 | Bacterial infections; effective for recovering the activities of beta-lactam antibiotics; 2-ethyl-3-methylmaleic acid dimethyl ester; maleic acid derivatives and/or dihydrofuranyl derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-8093294-B2 | Bacterial infections; effective for recovering the activities of beta-lactam antibiotics; 2-ethyl-3-methylmaleic acid dimethyl ester; maleic acid derivatives and/or dihydrofuranyl derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| EP-1941873-A1 | METALLO-BETA-LACTAMASE INHIBITOR | MEIJI SEIKA KAISHA LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | ME1, MGAM, GAA | CYP4F2 1625/4885CYP4A11 1497/4885DRD2 4635/4885 |
| US-12251370-B2 | Small molecule inhibitors of the BfrB:Bfd interaction | BLVRB, TFPI, ETFB | CYP4F2 242/4885CYP4A11 3088/4885DRD2 2418/4885 |
| US-20120071457-A1 | METALLO-BETA-LACTAMASE INHIBITORS | ME1, MGAM, GAA | CYP4F2 1625/4885CYP4A11 1497/4885DRD2 4635/4885 |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | ME1, MGAM, MANBA | CYP4F2 1614/4885CYP4A11 1459/4885DRD2 4668/4885 |
| US-20220031661-A1 | SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION | BLVRB, TFPI, ETFB | CYP4F2 242/4885CYP4A11 3088/4885DRD2 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.