SCHEMBL305300

SCHEMBL305300

O=C(O)COc1ccccc1N(CC(=O)O)CC(=O)O

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.78
L3MBTL1 Q9Y468 2/20 0.54
POLB P06746 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GLA P06280 1/20 0.54
PTGDR2 Q9Y5Y4 7/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
ALOX15 P16050 1/20 0.48
CD69 Q07108 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907230 1.00 TDP1 (0.78) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL17640371 0.89 TDP1 (0.71) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL232103 0.88 TDP1 (1.00) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL31185081 0.88 TDP1 (1.00) TDP1L3MBTL1POLBSMN1; SMN2GLA
Ethane SCHEMBL28264318 0.85 TDP1 (0.93) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL28908699 0.81 TDP1 (0.53) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL30167509 0.81 PKM (0.59) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL17640377 0.81 TDP1 (0.85) TDP1L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL3651761 0.81 TDP1 (0.70) TDP1L3MBTL1POLBSMN1; SMN2
SCHEMBL13560703 0.80 TDP1 (0.82) TDP1POLBSMN1; SMN2PTGDR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10933146-B2 Cell-permeable imaging sensors and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-03-02 US claimed
US-10451640-B2 Iron (II) ion detection agent and detection method using same CELLSPECT CO., LTD. (JP) 2019-10-22 US claimed
US-20190184036-A1 CELL-PERMEABLE IMAGING SENSORS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-06-20 US claimed
US-20160356796-A1 IRON (II) ION DETECTION AGENT AND DETECTION METHOD USING THE SAME METALLOGENICS CO., LTD. (JP) 2016-12-08 US claimed
EP-3096143-A1 IRON(II) ION DETECTION AGENT AND DETECTION METHOD USING SAME Metallogenics Co., Ltd. (JP) 2016-11-23 EP claimed
EP-2045252-B1 Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings LIFE TECHNOLOGIES CORP (US) 2013-05-01 EP claimed
EP-1311487-B1 DERIVATIVES OF 1,2-DIHYDRO-7-HYDROXYQUINOLINES CONTAINING FUSED RINGS MOLECULAR PROBES INC (US) 2008-11-26 EP claimed
EP-0750678-B1 NOVEL METHOD FOR THE CONDITIONING OF LIQUID SAMPLES FOSS ELECTRIC AS (DK) 1999-09-08 EP claimed
EP-3833715-B1 SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES LIFE TECHNOLOGIES CORP (US) 2026-01-07 EP disclosed
US-20250199009-A1 CLICK-CHEMISTRY FUNCTIONALIZED COMPOUNDS AND METHODS OF CONJUGATION AAT BIOQUEST, INC. 2025-06-19 US disclosed
US-12297383-B2 Condensed polycyclic conjugated polymers and their use for biological detection AAT BIOQUEST, INC. (US) 2025-05-13 US disclosed
US-12258477-B2 Silicon-substituted rhodamine dyes and dye conjugates Life Technologies Corporation (US) 2025-03-25 US disclosed
US-20240052238-A1 CONDENSED POLYCYCLIC CONJUGATED POLYMERS AND THEIR USE FOR BIOLOGICAL DETECTION AAT BIOQUEST, INC. (US) 2024-02-15 US disclosed
US-11827824-B2 Condensed polycyclic conjugated polymers and their use for biological detection AAT BIOQUEST, INC. (US) 2023-11-28 US disclosed
US-5696157-A Sulfonated derivatives of 7-aminocoumarin MOLECULAR PROBES, INC. (US) 1997-12-09 US disclosed
US-5627015-A PROCESSING SOLUTION WITH BLEACHING ABILITY AFTER COLOR DEVELOPMENT WITH FERRIC COMPLEX SALT AND AN IMINE CARBOXYLIC ACID OR HETEROCYCLIC CARBOXYLIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1997-05-06 US disclosed
EP-0695969-A1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-02-07 EP disclosed
EP-0657777-A2 Method for processing silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1995-06-14 EP disclosed
EP-0649057-A2 A photographic processing composition and a processing process therewith FUJI PHOTO FILM CO., LTD. (JP) 1995-04-19 EP disclosed
US-5338649-A Using biodegradable metal chelate compound as bleaching agent FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250199009-A1 CLICK-CHEMISTRY FUNCTIONALIZED COMPOUNDS AND METHODS OF CONJUGATION CTTN, PTMS, HLCS TDP1 859/4885L3MBTL1 1203/4885POLB 3672/4885
US-12258477-B2 Silicon-substituted rhodamine dyes and dye conjugates SRI, SI, IK TDP1 4224/4885L3MBTL1 1602/4885POLB 4368/4885
US-20190184036-A1 CELL-PERMEABLE IMAGING SENSORS AND USES THEREOF NCS1, CASR, CHERP TDP1 2278/4885L3MBTL1 2384/4885POLB 4845/4885
US-10451640-B2 Iron (II) ion detection agent and detection method using same NR0B1, SLC40A1, NR0B2 TDP1 4701/4885L3MBTL1 1802/4885POLB 3914/4885
US-10933146-B2 Cell-permeable imaging sensors and uses thereof NCS1, CASR, CHERP TDP1 2278/4885L3MBTL1 2384/4885POLB 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.