Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28973045 | 0.78 | ACHE (0.48) | MAOAMAOBACHEBACE1ALDH1A1 | |
| SCHEMBL11134940 | 0.77 | MAOA (0.44) | MAOAMAOBACHEBACE1ALDH1A1 | |
| Acetic Acid SCHEMBL27348090 | 0.74 | ACHE (0.48) | MAOAMAOBACHEBACE1ALDH1A1 | |
| SCHEMBL27996831 | 0.74 | ACHE (0.44) | MAOAMAOBACHEBACE1ALDH1A1 | |
| SCHEMBL1672539 | 0.74 | ACHE (0.58) | MAOAMAOBACHEBACE1MAPT | |
| SCHEMBL5145016 | 0.73 | MAOA (0.48) | MAOAMAOBACHEBACE1ALDH1A1 | |
| SCHEMBL10766402 | 0.72 | ACHE (0.61) | MAOAMAOBACHEBACE1MAPT | |
| SCHEMBL11492402 | 0.72 | MAOA (0.44) | MAOAMAOBACHEBACE1ALDH1A1 | |
| SCHEMBL7915011 | 0.72 | ACHE (0.61) | MAOAMAOBACHEBACE1ALDH1A1 | |
| SCHEMBL15071872 | 0.72 | MAOA (0.64) | MAOAMAOBACHEBACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |
| CN-1043177-A | Carry out the method for dyeing keratinous fibres and new 1,4-benzoquinones with oxyindole and quinone derivative | OREAL (FR) | 1990-06-20 | — | — | CN | claimed |
| US-10695342-B2 | Methods and compositions for preventing opioid abuse | ALBANY MOLECULAR RESEARCH, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-20170157116-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | CURIA BUFFALO R&D, LLC | 2017-06-08 | — | — | US | disclosed |
| EP-2189468-B1 | METHOD FOR MODIFICATION OF NUCLEOTIDES IN NUCLEIC ACID, AND NUCLEIC ACID HAVING MODIFIED NUCLEOTIDE THEREIN | KEK HIGH ENERGY ACCELERATOR (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-8815539-B1 | Methods for producing melanin and inorganic fertilizer from fermentation leachates | River Road Research, Inc. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8492536-B2 | Method for modifying nucleic acid bases, and nucleic acid base-modified product | INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTE OF NATURAL SCIENCES (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20100222563-A1 | METHOD FOR MODIFICATION OF NUCLEOTIDES IN NUCLEIC ACID, AND NUCLEIC ACID HAVING MODIFIED NUCLEOTIDE THEREIN | INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTE OF NATURAL SCIENCES (JP) | 2010-09-02 | — | — | US | disclosed |
| EP-2189468-A1 | METHOD FOR MODIFICATION OF NUCLEOTIDES IN NUCLEIC ACID, AND NUCLEIC ACID HAVING MODIFIED NUCLEOTIDE THEREIN | Inter-University Research Institute Corporation National Institutes of Natural Sciences (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0603322-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. | OREAL (FR) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993005018-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | L'OREAL (FR) | 1993-03-18 | — | — | WO | disclosed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |
| EP-0376776-B1 | PROCESS FOR DYEING KERATINOUS FIBRES WITH HYDROXYINDOLE ASSOCIATED WITH QUINONE AND 1,4-BENZOQUINONE | L'OREAL (FR) | 1992-09-23 | — | — | EP | disclosed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | disclosed |
| US-5053053-A | PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES | L'OREAL (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10695342-B2 | Methods and compositions for preventing opioid abuse | OPRM1, OPRK1, OPRD1 | MAOA 25/4885MAOB 22/4885ACHE 9/4885 |
| US-20100222563-A1 | METHOD FOR MODIFICATION OF NUCLEOTIDES IN NUCLEIC ACID, AND NUCLEIC ACID HAVING MODIFIED NUCLEOTIDE THEREIN | NSUN2, ADAR, NT5C3B | MAOA 3274/4885MAOB 2438/4885ACHE 4541/4885 |
| US-20170157116-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | OPRM1, OPRK1, OPRD1 | MAOA 25/4885MAOB 22/4885ACHE 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.