SCHEMBL30656233

SCHEMBL30656233

Cc1sc2ccc(OCc3cccnc3C(F)(F)F)cc2c1C(=O)NC1CN(C)CC1(F)F

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 7/20 0.37
SSTR1 P30872 3/20 0.36
MMP12 P39900 4/20 0.32
MMP13 P45452 3/20 0.32
MMP1 P03956 2/20 0.31
ADAM17 P78536 2/20 0.31
CD38 P28907 1/20 0.31
HSD17B13 Q7Z5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24484967 0.85 SLC26A4 (0.43) SSTR4
SCHEMBL30656337 0.85 SSTR4 (0.42) SSTR4SSTR1
SCHEMBL30656064 0.85 SLC6A5 (0.45) SSTR4SSTR1
SCHEMBL30656343 0.85 CFD (0.36) ADAM17CD38
SCHEMBL30655972 0.84 EDNRA (0.41) MMP12MMP1
SCHEMBL30714678 0.82 SSTR4 (0.38) SSTR4SSTR1MMP12MMP13ADAM17
SCHEMBL30656031 0.82 ESR1 (0.32) MMP12MMP13
SCHEMBL30656331 0.82 ALDH1A1 (0.38) CD38
SCHEMBL30656001 0.80 RAB9A (0.45)
SCHEMBL30656066 0.79 SCN9A (0.35) MMP13ADAM17CD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed