Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700502 | 0.85 | TEAD1 (0.39) | FAAHP2RX7 | |
| SCHEMBL30700175 | 0.83 | KCNH2 (0.41) | ENPP2P2RX7 | |
| SCHEMBL30699915 | 0.82 | TEAD1 (0.41) | FAAHENPP2 | |
| SCHEMBL30700088 | 0.82 | MGLL (0.41) | — | |
| SCHEMBL30699918 | 0.82 | MGLL (0.41) | — | |
| SCHEMBL30700033 | 0.78 | TACR1 (0.38) | ENPP2P2RX7 | |
| SCHEMBL25325576 | 0.71 | FAAH (0.36) | FAAHNOS3NOS1NOS2P2RX7 | |
| SCHEMBL30553285 | 0.71 | FAAH (0.36) | FAAHNOS3NOS1NOS2P2RX7 | |
| SCHEMBL30699948 | 0.70 | MGLL (0.43) | — | |
| SCHEMBL30700677 | 0.69 | MGLL (0.40) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |