SCHEMBL30717580

SCHEMBL30717580

CC(C)(C)OC(=O)N1CC2CCC(C1)N2c1nc2c(s1)CNCC2(C)C

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 6/20 0.36
CRBN Q96SW2 6/20 0.36
GPR119 Q8TDV5 1/20 0.35
NR1H2 P55055 2/20 0.35
USP30 Q70CQ3 1/20 0.33
SPR P35270 1/20 0.33
PIK3CA P42336 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
RET P07949 1/20 0.31
FPR2 P25090 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717715 0.89 DDB1 (0.35) DDB1CRBNGPR119NR1H2USP30
SCHEMBL30717646 0.85 MTOR (0.33) DDB1CRBNGPR119NR1H2USP30
SCHEMBL30717608 0.80 DDB1 (0.37) DDB1CRBNGPR119NR1H2USP30
SCHEMBL30717643 0.79 NR1H2 (0.37) DDB1CRBNGPR119NR1H2USP30
SCHEMBL30717574 0.78 SPR (0.37) DDB1CRBNGPR119NR1H2USP30
SCHEMBL30717589 0.74 IL1B (0.36) DDB1CRBNGPR119NR1H2USP30
SCHEMBL31254490 0.70 GPR119 (0.55) GPR119USP30MAPT
SCHEMBL30717623 0.69 SMN1; SMN2 (0.39) USP30
SCHEMBL30717657 0.69 ADORA1 (0.35) GPR119USP30SPRKDM4EMAPT
SCHEMBL30717613 0.69 GRAMD1A (0.41) GPR119USP30SPRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
WO-2024038128-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS MIRONID LIMITED (GB) 2024-02-22 WO disclosed