Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.31 |
| ▸ | PIK3R3 | Q92569 | 2/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30717715 | 0.94 | DDB1 (0.35) | GPR119DDB1CRBNPIK3CAUSP30 | |
| SCHEMBL30717580 | 0.85 | DDB1 (0.36) | GPR119DDB1CRBNPIK3CAUSP30 | |
| SCHEMBL30717608 | 0.77 | DDB1 (0.37) | GPR119DDB1CRBNPIK3CAPIK3R1 | |
| SCHEMBL30717574 | 0.73 | SPR (0.37) | GPR119DDB1CRBNPIK3CAUSP30 | |
| SCHEMBL30717643 | 0.69 | NR1H2 (0.37) | GPR119DDB1CRBNUSP30NR1H2 | |
| SCHEMBL30717589 | 0.66 | IL1B (0.36) | GPR119DDB1CRBNUSP30NR1H2 | |
| SCHEMBL31254490 | 0.66 | GPR119 (0.55) | GPR119SMN1; SMN2USP30 | |
| SCHEMBL30717623 | 0.66 | SMN1; SMN2 (0.39) | SMN1; SMN2USP30 | |
| SCHEMBL30717657 | 0.65 | ADORA1 (0.35) | MTORGPR119USP30SPR | |
| SCHEMBL30717613 | 0.65 | GRAMD1A (0.41) | GPR119USP30SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572762-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | Mironid Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038128-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |