Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27373435 | 0.87 | LMNA (0.48) | ALDH1A1KLKB1HSD17B10LMNANPC1 | |
| SCHEMBL30736715 | 0.85 | RIPK1 (0.47) | KLKB1HSD17B10 | |
| SCHEMBL30736811 | 0.81 | KDM4E (0.51) | EPHB4TEKKDM4EALDH1A1KLKB1 | |
| SCHEMBL24208428 | 0.79 | GRM2 (0.50) | EPHB4TEKKDM4EALDH1A1KLKB1 | |
| SCHEMBL4018058 | 0.78 | HSD17B10 (0.57) | EPHB4TEKKDM4EALDH1A1KLKB1 | |
| SCHEMBL27373751 | 0.78 | P2RX7 (0.41) | KLKB1 | |
| SCHEMBL23297258 | 0.78 | CES2 (0.47) | KDM4EALDH1A1LMNANPC1MAPT | |
| SCHEMBL27286166 | 0.77 | KDM4E (0.49) | EPHB4TEKKDM4EALDH1A1KLKB1 | |
| SCHEMBL27286146 | 0.77 | MAOB (0.47) | EPHB4TEKKDM4EALDH1A1KLKB1 | |
| SCHEMBL30589683 | 0.76 | GRM2 (0.47) | KDM4EALDH1A1KLKB1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561575-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |