SCHEMBL30736715

SCHEMBL30736715

O=C(ON1C(=O)CCC1=O)c1cnn(Cc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.47
KLKB1 P03952 5/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
SCD5 Q86SK9 1/20 0.43
CREBBP Q92793 2/20 0.43
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2B Q13224 1/20 0.43
HSD17B10 Q99714 1/20 0.42
NAMPT P43490 1/20 0.42
HDAC3 O15379 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
MGLL Q99685 1/20 0.40
RPS6KA3 P51812 1/20 0.40
RPS6KA2 Q15349 1/20 0.40
RPS6KA1 Q15418 1/20 0.40
RPS6KA6 Q9UK32 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27373435 0.88 LMNA (0.48) KLKB1CREBBPGRIN1GRIN2BHSD17B10
SCHEMBL30736675 0.85 EPHB4 (0.40) KLKB1HSD17B10
SCHEMBL6426563 0.79 KLKB1 (0.53) RIPK1KLKB1L3MBTL1SCD5CREBBP
SCHEMBL3765456 0.79 KLKB1 (0.53) KLKB1L3MBTL1SCD5CREBBPPOLB
SCHEMBL27372319 0.78 ADRA1A (0.35) RIPK1KLKB1L3MBTL1SCD5CREBBP
SCHEMBL553848 0.76 ALDH1A1 (0.60) KLKB1L3MBTL1CREBBPTDP1
SCHEMBL553830 0.76 L3MBTL1 (0.62) RIPK1KLKB1L3MBTL1SCD5CREBBP
SCHEMBL950077 0.75 L3MBTL1 (0.56) RIPK1KLKB1L3MBTL1SCD5CREBBP
SCHEMBL19309377 0.74 KMT2A (0.53) POLBTDP1MGLL
SCHEMBL133554 0.74 KMT2A (0.53) POLBTDP1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561575-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed