Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748722 | 0.88 | TTBK1 (0.38) | JAK3POLBTTBK1TTBK2PRKDC | |
| SCHEMBL30749038 | 0.82 | ADORA3 (0.39) | ADORA3JAK3POLBMAPTNPC1 | |
| SCHEMBL30749100 | 0.81 | PRKDC (0.42) | PRKDCMAPTRAB9AALDH1A1 | |
| SCHEMBL30749058 | 0.77 | ADORA3 (0.36) | ADORA3JAK3POLBMAPTRAB9A | |
| SCHEMBL30748952 | 0.74 | SYK (0.37) | JAK3POLBMAPTNPC1RAB9A | |
| SCHEMBL30748787 | 0.73 | L3MBTL1 (0.36) | JAK3POLBMAPTRAB9AHTT | |
| SCHEMBL30748933 | 0.71 | SYK (0.40) | JAK3MAPTL3MBTL1GAAKDM4E | |
| SCHEMBL30749016 | 0.71 | SYK (0.36) | JAK3L3MBTL1JAK2JAK1ALDH1A1 | |
| SCHEMBL30748860 | 0.70 | RAD52 (0.33) | ADORA3MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL30748754 | 0.69 | XDH (0.36) | MAPTHTTL3MBTL1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |