Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764728 | 0.83 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1HSD11B1 | |
| SCHEMBL30764749 | 0.80 | HSD11B1 (0.49) | SIGMAR1KMT2AHSD11B1CYP2C19MEN1 | |
| SCHEMBL30764719 | 0.79 | SMN1; SMN2 (0.53) | SIGMAR1ALDH1A1HSD11B1 | |
| SCHEMBL30764734 | 0.75 | KMT2A (0.54) | KMT2AHSD11B1MEN1KCNH2 | |
| SCHEMBL30764724 | 0.75 | HSD11B1 (0.51) | KDM4EALDH1A1KMT2AHSD11B1CYP2C19 | |
| SCHEMBL30764720 | 0.75 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1HSD11B1 | |
| SCHEMBL30764705 | 0.75 | EPHX2 (0.45) | KDM4EALOX15ALDH1A1KMT2AHSD11B1 | |
| SCHEMBL30764707 | 0.74 | HSD11B1 (0.55) | SIGMAR1KDM4EALDH1A1KMT2AHSD11B1 | |
| SCHEMBL30764756 | 0.74 | HSD11B1 (0.47) | KDM4EALDH1A1KMT2AHSD11B1MEN1 | |
| SCHEMBL30764764 | 0.73 | ALDH1A1 (0.49) | SIGMAR1KDM4EALDH1A1HSD11B1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |