Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764719 | 0.93 | SMN1; SMN2 (0.53) | SIGMAR1SMN1; SMN2MAPTALDH1A1HSD11B1 | |
| SCHEMBL30764720 | 0.89 | SIGMAR1 (0.60) | SIGMAR1SMN1; SMN2DRD2MAPTALDH1A1 | |
| SCHEMBL30764745 | 0.83 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1HSD11B1 | |
| SCHEMBL30764706 | 0.82 | L3MBTL1 (0.57) | SIGMAR1SMN1; SMN2MAPTALDH1A1HSD11B1 | |
| SCHEMBL30764724 | 0.81 | HSD11B1 (0.51) | SMN1; SMN2ALDH1A1HSD11B1HPGDLMNA | |
| SCHEMBL30764734 | 0.78 | KMT2A (0.54) | DRD2HSD11B1 | |
| SCHEMBL30764749 | 0.74 | HSD11B1 (0.49) | SIGMAR1MAPTHSD11B1 | |
| SCHEMBL30764755 | 0.74 | GAA (0.54) | SMN1; SMN2DRD2MAPTALDH1A1HSD11B1 | |
| SCHEMBL30764757 | 0.74 | HSD11B1 (0.46) | SMN1; SMN2ALDH1A1HSD11B1HPGDGHSR | |
| SCHEMBL30764707 | 0.73 | HSD11B1 (0.55) | SIGMAR1SMN1; SMN2ALDH1A1HSD11B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |