Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765733 | 0.91 | KMT2A (0.36) | KMT2ALMNAKDM4EALDH1A1HDAC6 | |
| SCHEMBL30765468 | 0.86 | LMNA (0.40) | KMT2ALMNAKDM4EALDH1A1TSHR | |
| SCHEMBL30765521 | 0.85 | KMT2A (0.38) | KMT2ALMNAKDM4EALDH1A1HDAC6 | |
| SCHEMBL30765729 | 0.82 | ALDH1A1 (0.38) | KMT2ALMNAKDM4EALDH1A1BACE1 | |
| SCHEMBL30765797 | 0.80 | KMT2A (0.40) | KMT2ALMNAF2KDM4EALDH1A1 | |
| SCHEMBL30765676 | 0.78 | SOS1 (0.41) | KMT2ALMNAKDM4EALDH1A1HDAC6 | |
| SCHEMBL30765893 | 0.78 | ALDH1A1 (0.33) | KMT2ALMNAKDM4EALDH1A1TSHR | |
| SCHEMBL30765920 | 0.77 | L3MBTL1 (0.41) | KMT2ALMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL30765712 | 0.77 | LMNA (0.35) | LMNAKDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL30765957 | 0.76 | ALDH1A1 (0.38) | KMT2ALMNAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |