SCHEMBL3076701

SCHEMBL3076701

O=C(Nc1ccccc1C(=O)OCC=Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
ACLY P53396 1/20 0.50
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP12 P39900 1/20 0.48
LMNA P02545 2/20 0.47
ALDH1A1 P00352 4/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
EGFR P00533 1/20 0.46
KDM4E B2RXH2 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CASP3 P42574 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076696 1.00 RAB9A (0.53) RAB9ANPC1ACLYMMP1MMP2
SCHEMBL4955339 0.85 L3MBTL1 (0.57) ACLYALDH1A1MAPTHPGDHTT
SCHEMBL4404890 0.83 TRPM2 (0.49) RAB9ANPC1ACLYMMP1MMP2
SCHEMBL4404884 0.83 TRPM2 (0.49) RAB9ANPC1ACLYMMP1MMP2
SCHEMBL27372484 0.81 ALDH1A1 (0.57) RAB9ANPC1ACLYMMP1MMP2
SCHEMBL27372482 0.81 ALDH1A1 (0.57) RAB9ANPC1ACLYMMP1MMP2
SCHEMBL10874779 0.79 NPC1 (0.68) RAB9ANPC1LMNAALDH1A1MAPT
SCHEMBL27513654 0.79 ACLY (0.53) ACLYMMP1MMP2MMP9MMP12
SCHEMBL9597291 0.79 ACLY (0.53) RAB9ANPC1ACLYMMP1MMP2
SCHEMBL2233522 0.77 NPC1 (0.69) RAB9ANPC1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795166-B2 Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method N.E. CHEMCAT CORPORATION (JP) 2010-09-14 US disclosed
US-20070155617-A1 FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD N. E. CHEMCAT CORPORATION (JP) 2007-07-05 US disclosed