SCHEMBL307768

SCHEMBL307768

Nc1ccc([N+](=O)[O-])cc1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.61
ALDH1A1 P00352 8/20 0.59
CYP3A4 P08684 3/20 0.59
HIF1A Q16665 1/20 0.59
TSHR P16473 3/20 0.57
GAA P10253 1/20 0.57
THRB P10828 1/20 0.57
HTT P42858 1/20 0.53
ALOX15 P16050 1/20 0.52
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29111475 0.98 TDP1 (0.59) TDP1ALDH1A1CYP3A4HIF1ATSHR
Nitrogen SCHEMBL28796125 0.96 TDP1 (0.57) TDP1ALDH1A1CYP3A4HIF1ATSHR
Phenol SCHEMBL27580206 0.86 GAA (0.57) TDP1ALDH1A1CYP3A4HIF1ATSHR
SCHEMBL589324 0.85 ALDH1A1 (0.62) TDP1ALDH1A1CYP3A4HIF1ATSHR
SCHEMBL28669131 0.84 MAPT (0.53) TDP1ALDH1A1CYP3A4HIF1ATSHR
SCHEMBL28252591 0.82 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4HIF1ATSHR
SCHEMBL85604 0.82 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4HIF1ATSHR
SCHEMBL29379039 0.82 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4HIF1ATSHR
Hydrochloric Acid SCHEMBL30306150 0.80 ALDH1A1 (0.67) TDP1ALDH1A1CYP3A4HIF1ATSHR
SCHEMBL4233404 0.80 HSPB1 (0.64) TDP1ALDH1A1CYP3A4HTTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US claimed
CN-114836997-B In-situ coupling color development method of meta-aramid fiber and obtained color development aramid fiber 浙江理工大学 2023-10-31 CN claimed
CN-115612097-B Low-dielectric and high-strength nanocomposite and preparation method thereof 江西有泽新材料科技有限公司 2023-10-03 CN claimed
CN-116769161-A Polyimide with low CTE and high light transmittance, diamine monomer thereof and preparation method thereof 河北科技大学 2023-09-19 CN claimed
CN-115612097-A Nano composite material with low dielectric constant and high strength and preparation method thereof 江西有泽新材料科技有限公司 2023-01-17 CN claimed
CN-114836997-A In-situ coupling color development method of meta-aramid and obtained color development aramid 浙江理工大学 2022-08-02 CN claimed
CN-112827368-A Anti-pollution reverse osmosis membrane and preparation method thereof 中化(宁波)润沃膜科技有限公司 2021-05-25 CN claimed
EP-4748837-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) 2026-05-27 EP disclosed
EP-4731306-A1 CYSTOBACTAMID DERIVATIVES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2026-04-29 EP disclosed
US-20250214964-A1 COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL) BENZAMIDE AND ANALOGUES AND USE THEREOF CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2025-07-03 US disclosed
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US disclosed
US-RE50453-E1 Indole derivatives as CFTR modulators VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-06-10 US disclosed
EP-4561999-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY Abbvie Operations Singapore Pte. Ltd. (SG) 2025-06-04 EP disclosed
US-4120693-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-17 US disclosed
US-4111681-A CYCLOALKANAPYRAZOLE-3-CARBONITRILE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-05 US disclosed
US-4108628-A Cycloalkanopyrazole herbicides mixtures E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-22 US disclosed
US-4060544-A COUPLERS GAF CORPORATION (US) 1977-11-29 US disclosed
US-4059434-A Cycloalkanapyrazole herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-11-22 US disclosed
US-4039524-A Keto-amido containing phenylazo benzothiazole dyestuffs GAF CORPORATION (US) 1977-08-02 US disclosed
US-3931145-A POLYESTER GAF CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214964-A1 COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL) BENZAMIDE AND ANALOGUES AND USE THEREOF ABAT, AADAT, AADAC TDP1 2567/4885ALDH1A1 314/4885CYP3A4 352/4885
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture NOS1, NOS3, NOS2 TDP1 2910/4885ALDH1A1 754/4885CYP3A4 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.