Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949224 | 0.85 | HSD17B10 (0.52) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL22499046 | 0.82 | METTL3 (0.47) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL23530592 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL23530739 | 0.79 | MEN1 (0.42) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL24737349 | 0.78 | MEN1 (0.43) | ALDH1A1MEN1PKMKMT2AADRA1D | |
| SCHEMBL29830221 | 0.77 | METTL3 (0.48) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL27030381 | 0.77 | METTL3 (0.48) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL9796680 | 0.76 | TDP1 (0.51) | KDM4EALDH1A1PKMNPC1RAB9A | |
| SCHEMBL8176725 | 0.76 | RAB9A (0.54) | KDM4EALDH1A1MEN1PKMKMT2A | |
| SCHEMBL9570362 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875026-B1 | IMIDAZOPYRIDINE DERIVATIVE USED IN THE TREATMENT OF DIABETES | METABRAIN RES (FR) | 2016-09-21 | — | — | EP | disclosed |
| EP-2875026-B1 | IMIDAZOPYRIDINE DERIVATIVE USED IN THE TREATMENT OF DIABETES | METABRAIN RES (FR) | 2016-09-21 | — | — | EP | disclosed |
| US-9381191-B2 | Imidazopyridine derivatives useful in treating diabetes | METABRAIN RESEARCH (FR) | 2016-07-05 | — | — | US | disclosed |
| US-9381191-B2 | Imidazopyridine derivatives useful in treating diabetes | METABRAIN RESEARCH (FR) | 2016-07-05 | — | — | US | disclosed |
| US-9381191-B2 | Imidazopyridine derivatives useful in treating diabetes | METABRAIN RESEARCH (FR) | 2016-07-05 | — | — | US | disclosed |
| US-20150182507-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL IN TREATING DIABETES | METABRAIN REDEARCH (FR) | 2015-07-02 | — | — | US | disclosed |
| US-20150182507-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL IN TREATING DIABETES | METABRAIN REDEARCH (FR) | 2015-07-02 | — | — | US | disclosed |
| US-20150182507-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL IN TREATING DIABETES | METABRAIN REDEARCH (FR) | 2015-07-02 | — | — | US | disclosed |
| US-20100227880-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-09-09 | — | — | US | disclosed |
| US-6863647-B2 | 2-Ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN S.P.A. (IT) | 2005-03-08 | — | — | US | disclosed |
| US-20040157827-A1 | 2-Ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PEVARELLO PAOLO (IT) | 2004-08-12 | — | — | US | disclosed |
| US-20030187040-A1 | 2-Ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2003-10-02 | — | — | US | disclosed |
| EP-1124811-A1 | 2-UREIDO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026203-A1 | 2-UREIDO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227880-A1 | CHEMICAL COMPOUNDS | CYP3A5, SLC10A1, ABCB11 | KDM4E 2460/4885ALDH1A1 210/4885MEN1 627/4885 |
| US-20030187040-A1 | 2-Ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | UCK2, ULK3, CDK2 | KDM4E 2087/4885ALDH1A1 903/4885MEN1 1294/4885 |
| US-20040157827-A1 | 2-Ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | UCK2, ULK3, CDK2 | KDM4E 2087/4885ALDH1A1 903/4885MEN1 1294/4885 |
| US-20150182507-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL IN TREATING DIABETES | IAPP, SLC5A2, GPR119 | KDM4E 3434/4885ALDH1A1 206/4885MEN1 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.